Results 21 to 30 of about 3,521 (274)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

10Gbit/s bias-free and error-free all-optical NRZ-OOK to RZ-OOK format conversion using a III-V-on-silicon microdisk resonator [PDF]

, 2012
C
Fedeli, Jean-Marc, Kumar, Rajesh, Mechet, Pauline, Morthier, Geert, Olivier, Nicolas, Regreny, Philippe, Roelkens, Günther, Spuesens, Thijs, Van Thourhout, Dries   +8 more
core   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

An interleaved high step‐up DC–DC converter based on coupled‐inductor

IET Power Electronics
This paper proposes an interleaved coupled‐inductor high step‐up direct current (DC)–DC converter. This converter uses a coupled inductor (CI), a voltage multiplier (VM) integrated with a regenerative passive lossless clamp circuit to enhance the voltage
Kamran Karimi, Ebrahim Babaei, Mehran Karimi, Darioush Alizadeh, Seyyed Mohammad Javad Mousavi   +4 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Hybrid switched‐capacitor‐based boost DC–DC converter with reduced voltage stress

The Journal of Engineering
This article presents the new hybrid switched‐capacitor (SC)‐based transformerless DC–DC converter with a high step‐up capability and common ground features.
Tan Luong Van, Thanh Hai Nguyen
doaj   +1 more source

A Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller

International Journal of Adaptive Control and Signal Processing, EarlyView.
Block Diagram of the Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller. ABSTRACT This article introduces a discrete‐time robust adaptive one‐sample‐ahead preview super‐twisting sliding mode controller. A stability analysis of the controller by Lyapunov criteria is developed to demonstrate its robustness in handling both ...
Guilherme Vieira Hollweg, Paulo Jefferson Dias de Oliveira Evald, Shivam Chaturvedi, Hilton Abilio Gründling, Rodrigo Varella Tambara, Wencong Su   +5 more
wiley   +1 more source

Component design procedure for LCC‐S wireless power transfer systems based on genetic algorithms and sensitivity analysis

IET Power Electronics
This paper introduces a novel approach for designing a Wireless Power Transfer (WPT) system with LCC‐S compensation. Since WPT systems operate under resonant conditions, even small deviations of the components from the nominal values can result in a ...
Fabio Corti, Matteo Intravaia, Alberto Reatti, Francesco Grasso, Emanuele Grasso, Alicia Triviño Cabrera   +5 more
doaj   +1 more source

Two- and Three-dimensional High Performance, Patterned Overlay Multi-chip Module Technology [PDF]

, 1993
A two- and three-dimensional multi-chip module technology was developed in response to the continuum in demand for increased performance in electronic systems, as well as the desire to reduce the size, weight, and power of space systems. Though developed
Lyke, James
core   +1 more source