Results 31 to 40 of about 4,477,185 (228)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A RISC-V Vector Processor With Simultaneous-Switching Switched-Capacitor DC-DC Converters in 28 nm FDSOI [PDF]

, 2016
This work demonstrates a RISC-V vector microprocessor implemented in 28 nm FDSOI with fully integrated simultaneous-switching switched-capacitor DC-DC (SC DC-DC) converters and adaptive clocking that generates four on-chip voltages between 0.45 and 1 V ...
Alon, E, Asanović, K, Avizienis, R, Bailey, S, Blagojević, M, Chen, PH, Chiu, PF, Flatresse, P, Jevtić, R, Keller, B, Kwak, J, Le, HP, Lee, Y, Nikolić, B, Puggelli, A, Richards, B, Sutardja, N, Waterman, A, Zimmer, B   +18 more
core   +1 more source

DENDRITIC CELL DIFFERENTIATION BLOCKED BY PRIMARY EFFUSION LYMPHOMA-RELEASED FACTORS IS PARTIALLY RESTORED BY INHIBITION OF P38 MAPK [PDF]

, 2010
To better understand the molecular mechanisms underlying the dendritic cell (DC) defects in cancer, we analyzed which signaling pathway is implicated in the abnormal monocyte differentiation into DC determined by the presence of Primary effusion lymphoma
CIRONE, Mara, DI RENZO, Livia Maria, FAGGIONI, Alberto, FRATI, Luigi, G. Borgia, G. Lucania, TRIVEDI, PANKAJ   +6 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Positive dc to positive dc converter Patent [PDF]

, 1969
Conversion of positive dc voltage to positive dc voltage of lower ...
Berry, E. H., Nola, F. J.
core   +1 more source

Drude weight and dc-conductivity of correlated electrons

, 1995
The Drude weight $D$ and the dc-conductivity $\sigma_{dc} (T)$ of strongly correlated electrons are investigated theoretically. Analytic results are derived for the homogeneous phase of the Hubbard model in $d = \infty$ dimensions, and for spinless ...
A. Georges, A. Georges, A. Georges, A. J. Millis, A. Khurana, B. S. Shastry, D. Baeriswyl, D. J. Scalapino, D. Vollhardt, D. Vollhardt, E. Dagotto, E. Halvorsen, E. Müller Hartmann, E. Müller Hartmann, G. Baym, G. S. Uhrig, G. Uhrig, H. Castella, H. J. Schulz, H. Schweitzer, J. A. Riera, J. Jaklič, J. Jaklič, J. M. Luttinger, J. Wagner, M. J. Rozenberg, M. Jarrell, M. Jarrell, M. Jarrell, P. Horsch, R. Kubo, R. Vlaming, T. Giamarchi, T. Pruschke, T. Pruschke, V. Janiš, W. Kohn, W. Metzner, W. Stephan, X. Y. Zhang   +39 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Linear-assisted DC/DC converters with modified current-mode control applied to photovoltaic solar systems [PDF]

, 2014
This article shows the proposal of a current-mode one-cycle control for linear-assisted DC/DC converters. Linearassisted DC/DC converters are structures that allow to take advantages of the two classic alternatives in the design of power supply systems ...
Martínez García, Herminio
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Antigen presenting capacity of murine splenic myeloid cells [PDF]

, 2017
BACKGROUND: The spleen is an important site for hematopoiesis. It supports development of myeloid cells from bone marrow-derived precursors entering from blood. Myeloid subsets in spleen are not well characterised although dendritic cell (DC) subsets are
Hey, Ying-Ying, O'Neill, Helen C, Quah, Benjamin   +2 more
core   +2 more sources