Results 211 to 220 of about 21,788 (303)

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu   +5 more
wiley   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

open access: yesInterdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu   +6 more
wiley   +1 more source

Germanium‐Based Mid‐Infrared Integrated Photonics

open access: yesLaser &Photonics Reviews, EarlyView.
The mid‐infrared (mid‐IR) spectral range is a part of the electromagnetic spectrum in which most of the molecules have vibrational and rotational resonances. Photonics integration in this wavelength range have thus seen a burst of interest in the recent years, mainly driven by applications related with the detection of chemical and biological ...
Delphine Marris‐Morini   +6 more
wiley   +1 more source

Non‐Uniform Programmable Photonic Waveguide Meshes

open access: yesLaser &Photonics Reviews, EarlyView.
Integrating defect cells into uniform hexagonal waveguide meshes overcomes the fundamental spectral and temporal limitations of programmable photonics. By leveraging the Vernier effect through non‐uniform coupled cavities, this architecture achieves a tenfold increase in free spectral range and ultra‐fast sampling times, paving the way for next ...
Cristina Catalá‐Lahoz, José Capmany
wiley   +1 more source

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