Results 21 to 30 of about 85,206 (267)
The Role of AI in Characterizing the DCM Phenotype [PDF]
Frontiers in Cardiovascular Medicine, 2021 Dilated Cardiomyopathy is conventionally defined by left ventricular dilatation and dysfunction in the absence of coronary disease. Emerging evidence suggests many patients remain vulnerable to major adverse outcomes despite clear therapeutic success of modern evidence-based heart failure therapy.
Clint Asher +13 more
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Multimeric RGD-Based Strategies for Selective Drug Delivery to Tumor Tissues
Pharmaceutics, 2023 RGD peptides have received a lot of attention over the two last decades, in particular to improve tumor therapy through the targeting of the αVβ3 integrin receptor.
Jordan Cossu +2 more
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Tuning the Coordination Environment of Ru(II) Complexes with a Tailored Acridine Ligand
MoleculesA novel tridentate ligand featuring an acridine core and pyrazole rings, namely 2,7- di-tert-butyl-4,5-di(pyrazol-1-yl)acridine, L, was designed and used to create two ruthenium(II) complexes: [RuL2](PF6)2 and [Ru(tpy)L](PF6)2.
Ali Awada +4 more
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Chemical Biology of G-quadruplex and i-motif DNA: use of topologically constrained DNA
Comptes Rendus. Chimie, 2023 Tetrameric DNA structures such as G-quadruplex (G4) and i-motif (i-DNA) have attracted increasing interest in the last decades. They are indeed involved in many biological processes including translation regulation, pre-mRNA processing, mRNA targeting ...
Dejeu, Jérôme, Defrancq, Eric
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NeuroImage, 2014 This technical note introduces a dynamic causal model (DCM) for resting state fMRI time series based upon observed functional connectivity--as measured by the cross spectra among different brain regions. This DCM is based upon a deterministic model that generates predicted crossed spectra from a biophysically plausible model of coupled neuronal ...
Karl J. Friston +3 more
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Frontiers in Chemistry, 2019 Multivalent structures displaying different instead of similar sugar units, namely heteroglycoclusters (hGCs), are stimulating the efforts of glycochemists for developing compounds with new biological properties.
David Goyard +4 more
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Rheology in Product Development: An Insight into 3D Printing of Hydrogels and Aerogels
Gels, 2023 Rheological characterisation plays a crucial role in developing and optimising advanced materials in the form of hydrogels and aerogels, especially if 3D printing technologies are involved.
Raquel V. Barrulas, Marta C. Corvo
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iScienceSummary: The activation of anticancer molecules with visible light constitutes an elegant strategy to target tumors and to improve the selectivity of treatments.
Zakaria Ziani +3 more
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Comparing hemodynamic models with DCM
NeuroImage, 2007 The classical model of blood oxygen level-dependent (BOLD) responses by Buxton et al. [Buxton, R.B., Wong, E.C., Frank, L.R., 1998. Dynamics of blood flow and oxygenation changes during brain activation: the Balloon model. Magn. Reson. Med. 39, 855-864] has been very important in providing a biophysically plausible framework for explaining different ...
Klaas Enno Stephan +4 more
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Prebiotic formation of thioesters via cyclic anhydrides as a key step in the emergence of metabolism
Scientific ReportsThioesters are high-energy derivatives of carboxylic acids that are essential in the functioning of today’s living cells. Their central role argues in favor of their early introduction in the abiotic reaction network which led to the emergence of life on
Abdelkarim El Qami +5 more
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