The requirement of cellularity for abiogenesis [PDF]
Computational and Structural Biotechnology Journal, 2021 The history of modern biochemistry started with the cellular theory of life. By putting aside the holistic protoplasmic theory, scientists of the XX century were able to advance the functional classification of cellular components significantly. The cell
Tetsuya Yomo
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The RNA-First Fallacy: Conflating Evolutionary Ancestry with Prebiotic Primacy [PDF]
LifeThe RNA-World hypothesis remains the most widely accepted framework in origins-of-life research, anchored in compelling biochemical evidence for RNA’s deep evolutionary ancestry.
Amit Kahana
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The Dissipative Photochemical Origin of Life: UVC Abiogenesis of Adenine
Entropy, 2021 The non-equilibrium thermodynamics and the photochemical reaction mechanisms are described which may have been involved in the dissipative structuring, proliferation and complexation of the fundamental molecules of life from simpler and more common ...
Karo Michaelian
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Molecular Dissipative Structuring: The Fundamental Creative Force in Biology [PDF]
EntropyThe spontaneous emergence of macroscopic dissipative structures in systems driven by generalized chemical potentials is well established in non-equilibrium thermodynamics.
Karo Michaelian
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Dissipative Photochemical Abiogenesis of the Purines
Entropy, 2022 We have proposed that the abiogenesis of life around the beginning of the Archean may have been an example of “spontaneous” microscopic dissipative structuring of UV-C pigments under the prevailing surface ultraviolet solar spectrum.
Karo Michaelian
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Amniotic Fluid and Ocean Water: Evolutionary Echoes, Chemical Parallels, and the Infiltration of Micro- and Nanoplastics [PDF]
ToxicsBackground: Abiogenesis is hypothesized to have occurred in the aquatic environments of the early Earth approximately 3.8–4.0 billion years ago, in oceans containing high concentrations of ions (Na+ ≈ 470 mmol/L, Cl− ≈ 545 mmol/L, Mg2+ ≈ 51–53 mmol/L ...
Antonio Ragusa
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The hierarchical organization of autocatalytic reaction networks and its relevance to the origin of life. [PDF]
PLoS Computational Biology, 2022 Prior work on abiogenesis, the emergence of life from non-life, suggests that it requires chemical reaction networks that contain self-amplifying motifs, namely, autocatalytic cores.
Zhen Peng, Jeff Linderoth, David A Baum
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Reproducible Ala-Gly oligomerization catalyzed by the natural Borate colemanite in prebiotic conditions [PDF]
Scientific ReportsThe abiogenesis of complex peptides is a yet unsolved problem concerning the origin of life, as it is unclear how specific amino acid sequences could be formed in the absence of a regulation mechanism.
Isabella Rimoldi +8 more
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Undefining life's biochemistry: implications for abiogenesis [PDF]
Journal of the Royal Society Interface, 2022 Stephen Freeland
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Exploring the space of self-reproducing ribozymes using generative models [PDF]
Nature CommunicationsEstimating the plausibility of RNA self-reproduction is central to origin-of-life scenarios. However, this property has been shown in only a handful of catalytic RNAs.
Camille N. Lambert +8 more
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