THE OCTOMORPHIC ORIGIN OF LIFE ABIOGENESIS
This paper presents a geometric mechanism for the origin of life based on the Octomorphic Framework. Instead of treating life as a chemical accident, the model shows how specific coherence structures emerge naturally from the geometry of matter. Using three core quantities — triangle-braidness (TB), phase strain (Delta L), and mean coherence curvature (
Simpson, Brian
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Exploring the space of self-reproducing ribozymes using generative models [PDF]
Nature CommunicationsEstimating the plausibility of RNA self-reproduction is central to origin-of-life scenarios. However, this property has been shown in only a handful of catalytic RNAs.
Camille N. Lambert +8 more
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Photochemical synthesis of natural lipids in artificial and living cells [PDF]
Nature CommunicationsLipid synthesis plays a central role in cell structure, signaling, and metabolism. A general method for the abiogenesis of natural lipids could transform the development of lifelike artificial cells and unlock new ways to explore lipid functions in ...
Peng Ji +6 more
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Potassium at the Origins of Life: Did Biology Emerge from Biotite in Micaceous Clay?
Life, 2022 Intracellular potassium concentrations, [K+], are high in all types of living cells, but the origins of this K+ are unknown. The simplest hypothesis is that life emerged in an environment that was high in K+.
Helen Greenwood Hansma
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Xeno Amino Acids: A Look into Biochemistry as We Do Not Know It
Life, 2023 Would another origin of life resemble Earth’s biochemical use of amino acids? Here, we review current knowledge at three levels: (1) Could other classes of chemical structure serve as building blocks for biopolymer structure and catalysis?
Sean M. Brown +2 more
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The “Odd Inches”: Moby-Dick’s Fossil Record and Melville’s Admeasured Time
Miranda: Revue Pluridisciplinaire du Monde Anglophone, 2022 This paper considers the measurements of fossils and markers of geologic time as they appear throughout Moby-Dick, complicating histories of bodies and their remainders. Looking for instances where Ishmael’s measurements fall short or fail to include the
Ryan Heryford
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Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics [PDF]
Open Biology, 2013 A sudden transition in a system from an inanimate state to the living state—defined on the basis of present day living organisms—would constitute a highly unlikely event hardly predictable from physical laws.
Robert Pascal +2 more
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The Future of Origin of Life Research: Bridging Decades-Old Divisions
Life, 2020 Research on the origin of life is highly heterogeneous. After a peculiar historical development, it still includes strongly opposed views which potentially hinder progress.
Martina Preiner +24 more
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Did Homocysteine Take Part in the Start of the Synthesis of Peptides on the Early Earth?
Biomolecules, 2022 Unlike its shorter analog, cysteine, and its methylated derivative, methionine, homocysteine is not today a proteinogenic amino acid. However, this thiol containing amino acid is capable of forming an activated species intramolecularly.
Sparta Youssef-Saliba +2 more
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Synthesis and Characterization of Amino Acid Decyl Esters as Early Membranes for the Origins of Life
Membranes, 2022 Understanding how membrane forming amphiphiles are synthesized and aggregate in prebiotic settings is required for understanding the origins of life on Earth 4 billion years ago.
Isabella Lago +3 more
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