Claudin-3 is expressed at the <i>macula densa</i> and is associated with altered glomerular filtration in claudin-3 knockout mice. [PDF]
Chassot A, Feraille E, Sassi A.
europepmc +1 more source
Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney +10 more
wiley +1 more source
Synthetic CT imaging for pelvic and abdominal MR-only radiotherapy: Clinical validation on a 1.5T MR-Linac. [PDF]
Gaban C +4 more
europepmc +1 more source
Trim32 regulates the transition from proliferation to differentiation in C2C12 cells after myogenic induction. We found that, at the onset of differentiation, Trim32 destabilizes c‐Myc mRNA, promotes cell cycle exit, and enables normal myotube formation.
Lu Xiong +6 more
wiley +1 more source
Stimulation of basolateral calcium-sensing receptor inhibits Kir4.1/Kir5.1 in the mouse distal convoluted tubule. [PDF]
Wang J +7 more
europepmc +1 more source
The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis
H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo +8 more
wiley +1 more source
Comparison of stationary digital chest tomosynthesis to portable chest radiographs: A patient study. [PDF]
Wing C +12 more
europepmc +1 more source
Bakuchiol: From structural mimicry to systems‐level skin biology
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley +1 more source
Single-cell spatial mapping of human kidney development implicates the microenvironment in guiding cell fate decisions. [PDF]
Levinsohn J +23 more
europepmc +1 more source

