Results 21 to 30 of about 683 (66)

Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications

MedComm, Volume 6, Issue 9, September 2025.
Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen, Jiachen Liu, Yinhuai Wang, Zebin Deng, Fei Deng   +4 more
wiley   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, Volume 58, Issue 9, September 2025.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Biomolecular Affinities and Cytotoxicity of Copper(I) and Silver(I) Phosphine–Pyridinyl Complexes Against CACO‐2 and CASKI Cell Lines

European Journal of Inorganic Chemistry, Volume 28, Issue 15, May 28, 2025.
This study reports Copper(I) and Silver(I) complexes with pyridinyl Schiff base ligands and triphenylphosphine. Their DNA/protein binding and in vitro cytotoxicity were evaluated. All complexes intercalated with calf thymus DNA, bound strongly to proteins, and showed notable cytotoxicity against Caco‐2 and Caski cancer cells, highlighting their promise
Adesola A. Adeleke, Miche D. Meyer, Nicole R. S. Sibuyi, Martin O. Onani, Bernard Omondi   +4 more
wiley   +1 more source

Hierarchically Porous SnO2/Cu Composites via Freeze Casting and Selective Cu Reduction

Advanced Engineering Materials, Volume 27, Issue 5, March 2025.
Lamellar SnO2/Cu foams are created by directional freeze casting of SnO2/CuO slurries followed by sintering and hydrogen reduction to achieve an interpenetrating SnO2‐30 vol% Cu structure. When applied as a negative electrode material for lithium‐ion batteries, the interaction between the mesoporous Cu phase and embedded SnO2 enables the reversible ...
Jean Pascal Fandré, Samuel Pennell, Sapna Lalitha Ramesh, Jeffrey Lopez, Ralph Spolenak, David Christophe Dunand   +5 more
wiley   +1 more source

Deep Learning‐Enhanced Chemiluminescence Vertical Flow Assay for High‐Sensitivity Cardiac Troponin I Testing

Small, Volume 21, Issue 11, March 19, 2025.
This study presents a chemiluminescence vertical flow assay (CL‐VFA) for high‐sensitivity detection of cardiac troponin I (cTnI), a critical biomarker for assessing myocardial infarction. By integrating innovations in CL‐based sensing, portable reader‐based imaging, and deep learning analysis, the CL‐VFA achieves rapid, cost‐effective, and precise ...
Gyeo‐Re Han, Artem Goncharov, Merve Eryilmaz, Shun Ye, Hyou‐Arm Joung, Rajesh Ghosh, Emily Ngo, Aoi Tomoeda, Yena Lee, Kevin Ngo, Elizabeth Melton, Omai B. Garner, Dino Di Carlo, Aydogan Ozcan   +13 more
wiley   +1 more source

Prevalence and factors associated with dementia in Lesotho: A cross‐sectional, population‐based study

Alzheimer's &Dementia, Volume 21, Issue 2, February 2025.
Abstract INTRODUCTION Limited research has examined dementia prevalence and associated factors in Lesotho. This study investigates dementia prevalence and the associated factors in Lesotho. METHODS A survey in Lesotho included 1738 participants screened for dementia and potential associated factors with a focus on modifiable factors.
Natalie E. Johnson, Jennifer M. Belus, Felix Gerber, Tristan T. Lee, Irene Ayakaka, Pearl Letsoela, Manthabiseng Molulela, Frédérique Chammartin, Alain Amstutz, Niklaus D. Labhardt   +9 more
wiley   +1 more source

UEG Week 2025 Moderated Posters

United European Gastroenterology Journal, Volume 13, Issue S8, Page S189-S802, October 2025.
wiley   +1 more source

UEG Week 2025 Poster Presentations

United European Gastroenterology Journal, Volume 13, Issue S8, Page S803-S1476, October 2025.
wiley   +1 more source

Engineering a heme-dependent tryptophan hydroxylase pathway in <i>E. coli</i> for enhanced melatonin production. [PDF]

Synth Syst Biotechnol
Zhang L, Yin G, Pan S, Zheng X, Zhou S, Du G, Li J, Chen J, Xu R, Kang Z.   +9 more
europepmc   +1 more source

Lysine-Targeting Inhibitors of Amyloidogenic Protein Aggregation: A Promise for Neurodegenerative Proteinopathies. [PDF]

JACS Au
Murakami K, Nguyen THV, Nagao C, Mizuguchi K, Bitan G.   +4 more
europepmc   +1 more source