Results 1 to 10 of about 432 (64)

The CRISPR-Cas9 knockout DDC SH-SY5Y in vitro model for AADC deficiency provides insight into the pathogenicity of R347Q and L353P variants: a cross-sectional structural and functional analysis. [PDF]

FEBS J
Here, we generated a DDC‐KO cellular model for studying aromatic amino acid decarboxylase (AADC) deficiency. This model was created using CRISPR‐Cas9 in the SH‐SY5Y neuroblastoma cell line and was validated through the absence of the dopamine product and an altered l‐dopa metabolite profile.
Carmona-Carmona CA, Bisello G, Franchini R, Lunardi G, Galavotti R, Perduca M, Ribeiro RP, Belviso BD, Giorgetti A, Caliandro R, Lievens PM, Bertoldi M.   +11 more
europepmc   +2 more sources

CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer´s disease. [PDF]

Nat Commun, 2023
Del Campo M, Vermunt L, Peeters CFW, Sieben A, Hok-A-Hin YS, Lleó A, Alcolea D, van Nee M, Engelborghs S, van Alphen JL, Arezoumandan S, Chen-Plotkin A, Irwin DJ, van der Flier WM, Lemstra AW, Teunissen CE.   +15 more
europepmc   +1 more source

Proteomic Analysis Reveals Molecular Differences in the Development of Gastric Cancer. [PDF]

Evid Based Complement Alternat Med, 2022
Dhondrup R, Zhang X, Feng X, Lobsang D, Hua Q, Liu J, Cuo Y, Zhuoma S, Duojie G, Duojie Caidan S, Gyal S.   +10 more
europepmc   +1 more source

CRISPR/Cas9-Mediated genomic knock out of tyrosine hydroxylase and yellow genes in cricket Gryllus bimaculatus. [PDF]

PLoS One, 2023
Bai Y, He Y, Shen CZ, Li K, Li DL, He ZQ.   +5 more
europepmc   +1 more source

Sensitivity of contact-tracing for COVID-19 in Thailand: a capture-recapture application. [PDF]

BMC Infect Dis, 2022
Lerdsuwansri R, Sangnawakij P, Böhning D, Sansilapin C, Chaifoo W, Polonsky JA, Del Rio Vilas VJ.   +6 more
europepmc   +1 more source

Genetic diversity and molecular evolution of Plasmodium vivax Duffy Binding Protein and Merozoite Surface Protein-1 in northwestern Thailand. [PDF]

Infect Genet Evol, 2023
Tapaopong P, da Silva G, Chainarin S, Suansomjit C, Manopwisedjaroen K, Cui L, Koepfli C, Sattabongkot J, Nguitragool W.   +8 more
europepmc   +1 more source

Tea as a Source of Biologically Active Compounds in the Human Diet. [PDF]

Molecules, 2021
Klepacka J, Tońska E, Rafałowski R, Czarnowska-Kujawska M, Opara B.   +4 more
europepmc   +1 more source

Dyadic coping and fear of cancer progression among patients with hepatocellular carcinoma and their spouses in China: An actor-partner interdependence model. [PDF]

Asia Pac J Oncol Nurs
Hu R, Lu H, Yu J, Zhu Z.
europepmc   +1 more source

Liver fibrosis negatively impacts in vivo gene transfer to murine hepatocytes. [PDF]

Nat Commun
Simoni C, Nozi J, Starinieri F, La Bella T, Manta E, Negri C, Biffi M, Norata R, Rocchi M, Sanvito F, Ronzitti G, Barbon E, Cantore A.   +12 more
europepmc   +1 more source

Diversity and molecular network patterns of symptom phenotypes. [PDF]

NPJ Syst Biol Appl, 2021
Shu Z, Wang J, Sun H, Xu N, Lu C, Zhang R, Li X, Liu B, Zhou X.   +8 more
europepmc   +1 more source