An Efficient CO2-Upcycling Platform Based on Engineered Halomonas TD with Enhanced Acetate-Utilizing Capacity via Adaptive Laboratory Evolution. [PDF]
An electrochemical system is designed to convert CO2 into CO2‐derived electrolytes (CDE), mainly containing acetate and formate. The underlying mechanism of acetate metabolism in Halomonas TD80 is explored via ALE. Engineered TD80 produced high‐yield diversified products from CDE.
Wang C +18 more
europepmc +2 more sources
Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets. [PDF]
Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Li G +13 more
europepmc +2 more sources
Atopic dermatitis: pathogenesis and therapeutic intervention. [PDF]
Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease, and its complex pathogenesis is closely linked to genetic and environmental factors, skin barrier dysfunction as well as immune dysfunction, which imposes a significant socioeconomic burden in all countries. The compromised function of the skin barrier leads to the release of alarm
Yue C +16 more
europepmc +2 more sources
Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
wiley +1 more source
Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du +5 more
wiley +1 more source
Abstract The emerging relationship between fintechs and banks has revealed antitrust's antiquation. At one time, scholars predicted that fintechs could democratize banking while providing a critical source of competition. But then banks began to acquire their digital rivals: about 900 acquisitions of fintechs have taken place since 2021.
Gregory Day, Lindsay Sain Jones
wiley +1 more source
Knowledge and Misconceptions About Parkinson’s Disease in Lebanon: A Cross‐Sectional Survey
Background Parkinson’s disease (PD) is a neurodegenerative disorder affecting brain structure and function. It is manifested by unintended movements, characterized by tremors, stiffness, and difficulty with balance and coordination. According to the statistics reported by the World Health Organization (WHO), the prevalence of PD has doubled over the ...
Noura El-Loubani +8 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Transporters
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source
Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications
Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen +4 more
wiley +1 more source

