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Results 31 to 40 of about 55,300 (116)

Tumor-derived circulating exosomal miR-342-5p and miR-574-5p as promising diagnostic biomarkers for early-stage Lung Adenocarcinoma

International Journal of Medical Sciences, 2020
Lung cancer has been the leading cause of cancer morbidity and mortality in recent years. Most lung cancers are often asymptomatic until advanced or metastatic stage.
Zhijun Han +11 more
semanticscholar +1 more source

Longterm Exercise-Derived Exosomal miR-342-5p: A Novel Exerkine for Cardioprotection

Circulation Research, 2019
Rationale: Exercise training, in addition to reducing cardiovascular risk factors, confers direct protection against myocardial ischemia/reperfusion injury and has been associated with improved heart attack survival in humans.
Zuoxu Hou +11 more
semanticscholar +1 more source

Framing consumer empowerment in the digital economy: From networks and engagement toward sustainable purchase

Business Ethics, the Environment &Responsibility, Volume 34, Issue 4, Page 1011-1032, October 2025.
Abstract The current study investigates the influence of variety among online providers and customers' access to knowledge on consumer networks, consumer engagement, and sustainable purchasing. Emphasis is on the underlying relationships among these constructs in the digital economy, which has evolved into a complex structure of multifarious nodes and ...
Elena‐Mădălina Vătămănescu +3 more
wiley +1 more source

Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications

MedComm, Volume 6, Issue 9, September 2025.
Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen +4 more
wiley +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, Volume 58, Issue 9, September 2025.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan +5 more
wiley +1 more source

Gene therapy for genetic diseases: challenges and future directions

MedComm, Volume 6, Issue 2, February 2025.
The graphical abstract provides an overview of gene therapy approaches, detailing the components of the therapy and the various delivery routes. Both in vivo and ex vivo strategies facilitate the implementation of gene replacement, gene suppression, gene supplementation, and gene editing.
Beibei Qie +4 more
wiley +1 more source

Revised Exon Structure of l-DOPA Decarboxylase (DDC) Reveals Novel Splice Variants Associated with Colorectal Cancer Progression

International Journal of Molecular Sciences, 2020
Colorectal cancer (CRC) is a highly heterogenous malignancy with an increased mortality rate. Aberrant splicing is a typical characteristic of CRC, and several studies support the prognostic value of particular transcripts in this malignancy.
P. Artemaki +7 more
semanticscholar +1 more source

Global trends in opioid use for pain management in acute pancreatitis: A multicentre prospective observational study

United European Gastroenterology Journal, Volume 12, Issue 8, Page 1114-1127, October 2024.
Abstract Background Since there is no current international consensus on the optimal approach for pain management in acute pancreatitis (AP), analgesic practices may vary across different healthcare settings. Objective This study explored global disparities in analgesic use, in particular opioids, during admission and at discharge in hospitalised AP ...
Cecilie Siggaard Knoph +371 more
wiley +1 more source

Advancements of non‐invasive imaging technologies for the diagnosis and staging of liver fibrosis: Present and future

VIEW, Volume 5, Issue 4, August 2024.
The authors provide an in‐depth exploration of recent advancements in ultrasound imaging, computed tomography imaging, magnetic resonance imaging, nuclear medicine imaging, radiomics, and artificial intelligence within the field of liver fibrosis research.
Wenpeng Huang, Yushuo Peng, Lei Kang
wiley +1 more source

Habitat opening fostered diversity: impact of dispersal and habitat‐shifts in the evolutionary history of a speciose afrotropical insect group

Ecography, Volume 2024, Issue 8, August 2024.
The opening of habitats associated with the emergence of C4 grasslands during the Neogene had a massive influence on the evolution of plant and animal communities. Strikingly, the impacts of grassland expansion on species diversification in Africa, where the largest surface of grasslands and savannas in the world is located, are not well understood. To
Noémie M.‐C. Hévin +10 more
wiley +1 more source

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