Results 1 to 10 of about 19 (19)

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes

British Journal of Pharmacology, Volume 180, Issue S2, Page S289-S373, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jurg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +28 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Transporters

British Journal of Pharmacology, Volume 180, Issue S2, Page S374-S469, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +27 more
wiley   +1 more source

The Patent Examiner Sweepstakes

American Business Law Journal, Volume 60, Issue 3, Page 599-650, Fall 2023., 2023
This article presents evidence that patent value varies with random examiner assignment at the U.S. Patent Office. Prior work analyzed firm growth as a function of review by “easy” examiners who grant patents at a high rate. The current research looks past whether a patent is granted and instead focuses on how assignment to an “easy” or “hard” examiner
W. Michael Schuster
wiley   +1 more source

Prognostic value of non‐invasive scores based on liver stiffness measurement, spleen diameter and platelets in HIV‐infected patients

Liver International, Volume 43, Issue 7, Page 1427-1439, July 2023., 2023
Abstract Background and Aims People living with HIV (PLWH) are at high risk for advanced chronic liver disease and related adverse outcomes. We aimed to validate the prognostic value of non‐invasive scores based on liver stiffness measurement (LSM) and on markers of portal hypertension (PH), namely platelets and spleen diameter, in PLWH.
Amine Benmassaoud, Juan Macias, Adèle Delamarre, Anaïs Corma‐Gomez, Giovanni Guaraldi, Jovana Milic, Jürgen K. Rockstroh, Kathrin Van Bremen, Emmanuel Tsochatzis, Akhilesh Mulay, Jennifer Price, Lucy J. Garvey, Maud Lemoine, Dana Kablawi, Bertrand Lebouche, Marina B. Klein, Luz R. Ballesteros, Christopher Boesecke, Filippo Schepis, Sanjay Bhagani, Graham Cooke, Annalisa Berzigotti, Kyoko Hirose, Juan A. Pineda, Agnihotram V. Ramanakumar, Victor De‐Ledinghen, Sahar Saeed, Giada Sebastiani   +27 more
wiley   +1 more source

Anatomy education for medical students in the United Kingdom and Republic of Ireland in 2019: A 20‐year follow‐up

Anatomical Sciences Education, Volume 15, Issue 6, Page 993-1006, November/December 2022., 2022
Abstract Anatomical education in the United Kingdom (UK) and Ireland has long been under scrutiny, especially since the reforms triggered in 1993 by the General Medical Council's “Tomorrow's Doctors.” The aim of the current study was to investigate the state of medical student anatomy education in the UK and Ireland in 2019.
Claire F. Smith, Samuel K. Freeman, David Heylings, Gabrielle M. Finn, D. Ceri Davies   +4 more
wiley   +1 more source

MicroRNA21 inhibition affects porcine oocyte maturation and alters protein expression critical for metabolic pathway function

Molecular Reproduction and Development, Volume 89, Issue 10, Page 443-458, October 2022., 2022
Abstract MicroRNA21 (MIR21) abundance in porcine oocytes and cumulus cells increases during in vitro maturation. The mechanism by which MIR21 regulates oocyte maturation and the effect on the developmental competence of subsequent embryos remains unclear.
Yunsheng Li, Malavika K. Adur, Steven M. Lonergan, Aileen F. Keating, Jason W. Ross   +4 more
wiley   +1 more source

Incidence of hypertension in people with HIV who are treated with integrase inhibitors versus other antiretroviral regimens in the RESPOND cohort consortium

HIV Medicine, Volume 23, Issue 8, Page 895-910, September 2022., 2022
Abstract Objective To compare the incidence of hypertension in people living with HIV receiving integrase strand transfer inhibitor (INSTI)‐based antiretroviral therapy (ART) versus non‐nucleoside reverse transcriptase inhibitors (NNRTIs) or boosted protease inhibitors (PIs) in the RESPOND consortium of HIV cohorts.
Dathan M. Byonanebye, Mark N. Polizzotto, Bastian Neesgaard, Mario Sarcletti, Raimonda Matulionyte, Dominique L. Braun, Antonella Castagna, Stéphane de Wit, Ferdinand Wit, Eric Fontas, Jörg Janne Vehreschild, Jan Vesterbacka, Lauren Greenberg, Camilla Hatleberg, Harmony Garges, Joel Gallant, Alain Volny Anne, Angela Öllinger, Iwona Mozer‐Lisewska, Bernard Surial, Vincenzo Spagnuolo, Coca Necsoi, Marc van der Valk, Amanda Mocroft, Matthew Law, Lene Ryom, Kathy Petoumenos, the RESPOND study group, M Hillebregt, N Rose, J Hutchinson, R Zangerle, H Appoyer, M Delforge, C Stephan, M Bucht, N Chkhartishvili, O Chokoshvili, C Mussini, V Borghi, C Pradier, K Dollet, C Caissotti, J Casabona, JM Miro, C Smith, F Lampe, M Johnson, F Burns, C Chaloner, A Lazzarin, A Poli, A Sönnerborg, K Falconer, V Svedhem, H Günthard, B Ledergerber, H Bucher, A Scherrer, JC Wasmuth, J Rockstroh, G Fätkenheuer, M Stecher, N Schulze, B Franke, Lene Ryom, J Rooney, I McNicholl, V Vannappagari, G Wandeler, J Lundgren, J Kowalska, D Raben, A Mocroft, L Peters, ED Williams, C Necsoi, A D’Arminio Monforte, A Bruguera, Nikos Dedes, Luis Mendao, JF Larsen, N Jaschinski, ML Jakobsen, T Bruun, A Bojesen, EV Hansen, AK Traytel, TW Elsing, D Kristensen, T Weide, L Bansi‐Matharu, A Pelchen‐Matthews   +92 more
wiley   +1 more source

Polygenic risk discriminates Lewy body dementia from Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 2, February 2025.
Abstract INTRODUCTION Lewy body dementia (LBD) shares genetic risk factors with Alzheimer's disease (AD), including apolipoprotein E (APOE), but is distinguishable at the genome‐wide level. Polygenic risk scores (PRS) may therefore improve diagnostic classification. METHODS We assessed diagnostic classification using AD‐PRS excluding APOE (AD‐PRSnoAPOE)
Anna McKeever, Peter Swann, Maura Malpetti, Paul C. Donaghy, Alan Thomas, Elijah Mak, Stephen F. Carter, Jerry H. K. Tan, Young T. Hong, Tim D. Fryer, Amanda Heslegrave, Henrik Zetterberg, Li Su, Leonidas Chouliaras, James B. Rowe, John T. O'Brien   +15 more
wiley   +1 more source

UEG Week 2023 Moderated Posters

, 2023
United European Gastroenterology Journal, Volume 11, Issue S8, Page 201-534, October 2023.
wiley   +1 more source

Estimated and in vivo measurements of bite force demonstrate exceptionally large bite forces in parrots (Psittaciformes)

Journal of Anatomy, Volume 246, Issue 2, Page 299-315, February 2025.
Bite force in parrots has been explored using data from muscle masses. The values were validated by comparison with data for bite force collected from live parrots. The parrot's reputation for a strong bite force is well founded. Abstract Jaw morphology and function determine the range of dietary items that an organism can consume.
Shannon L. Harrison, Gregory P. Sutton, Anthony Herrel, D. Charles Deeming   +3 more
wiley   +1 more source