Melatonin-Producing Microorganisms: A Rising Research Interest in Their Melatonin Biosynthesis and Effects on Crops. [PDF]
ABSTRACT Melatonin is imperative in animals and plants, contributing to multiple physiological roles, and its microbial production could offer an eco‐friendly alternative to synthetic melatonin. However, detecting and characterizing it in microorganisms remains ongoing, and the biosynthesis pathways are still poorly explored.
Kang SM +5 more
europepmc +2 more sources
Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets. [PDF]
Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Li G +13 more
europepmc +2 more sources
Atopic dermatitis: pathogenesis and therapeutic intervention. [PDF]
Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease, and its complex pathogenesis is closely linked to genetic and environmental factors, skin barrier dysfunction as well as immune dysfunction, which imposes a significant socioeconomic burden in all countries. The compromised function of the skin barrier leads to the release of alarm
Yue C +16 more
europepmc +2 more sources
Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du +5 more
wiley +1 more source
MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection
MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani +6 more
wiley +1 more source
Abstract The emerging relationship between fintechs and banks has revealed antitrust's antiquation. At one time, scholars predicted that fintechs could democratize banking while providing a critical source of competition. But then banks began to acquire their digital rivals: about 900 acquisitions of fintechs have taken place since 2021.
Gregory Day, Lindsay Sain Jones
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Transporters
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source
Impact assessment of earthquake early warning systems in Central America
Earthquake Early Warning (EEW) systems aim to alert users in advance of imminent shaking, enabling them to take action. In collaboration with local seismic agencies, the Swiss Seismological Service (SED), has developed national EEW systems across Central America.
Benazir Orihuela +8 more
wiley +1 more source
Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications
Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen +4 more
wiley +1 more source

