Results 21 to 30 of about 753,406 (101)

Organ Transplantation: Current Status, Challenges, and Future Prospects

open access: yesMedComm, Volume 7, Issue 1, January 2026.
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley   +1 more source

Addition of Neuromuscular Electrical Stimulation, Based on the Level of Excitability, to an Intradialytic Twice‐Weekly Cycling Protocol: A Randomized Trial

open access: yesPhysiotherapy Research International, Volume 31, Issue 1, January 2026.
ABSTRACT Background and Purpose Neuromuscular electrical stimulation (NMES) has shown promise as an adjunct or alternative to traditional training, but its optimal application in chronic kidney disease (CKD) population remains uncertain. This study aimed to compare the effects of the NMES intradialytic protocol combined with a traditional cycling on ...
Beatriz da Costa Ferreira   +6 more
wiley   +1 more source

Towards a Sustainable Future: Addressing Climate Change and Promoting Sustainable Development

open access: yesSustainable Development, Volume 34, Issue S1, Page 226-247, January 2026.
ABSTRACT This study aims to analyze policy research and global agreements on the decarbonization of economic development. Climate change and economic development are separate and equal, and strategies should separate responsibility from action. This will be required beyond the Kyoto and Paris agreements.
Woo‐Sik Sohn
wiley   +1 more source

Effect of High‐Pressure Processing Operating Parameters on Microbial Inactivation and Bioactive Protein Preservation in Bovine Milk: A Systematic Review

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT In the U.S., bovine milk is processed using thermal pasteurization to ensure microbial safety. However, this process alters the structure of heat‐sensitive bioactive proteins associated with the functional benefits of raw milk, including antimicrobial, immunomodulatory, and antioxidant proteins.
Rudy Sykora   +5 more
wiley   +1 more source

Electrochemical Characterization of Site‐Specifically Metal‐Modified DNA Films on Gold Electrode Surfaces

open access: yesChemPlusChem, Volume 90, Issue 12, December 10, 2025.
DNA films containing different CuII‐ or AgI‐mediated base pairs are investigated with respect to their electrochemical properties and how these depend on the size and charge of the artificial metal‐binding nucleobase as well as the location of the metal‐mediated base pair within the duplex.
Nils Flothkötter   +4 more
wiley   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, Volume 9, Issue 12, December 2025.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Pre‐fire structure drives variability in post‐fire aboveground carbon and fuel profiles in wet temperate forests

open access: yesEcosphere, Volume 16, Issue 12, December 2025.
Abstract Biological legacies (i.e., materials that persist following disturbance; “legacies”) shape ecosystem functioning and feedbacks to future disturbances, yet how legacies are driven by pre‐disturbance ecosystem state and disturbance severity is poorly understood—especially in ecosystems influenced by infrequent and severe disturbances.
Jenna E. Morris   +6 more
wiley   +1 more source

Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Gege Li   +13 more
wiley   +1 more source

Oral pretreatment with Escherichia coli Nissle 1917 enhances the host's defense against influenza A virus infection

open access: yesmLife, Volume 4, Issue 6, Page 664-680, December 2025.
Abstract Influenza A viruses (IAVs) pose a significant threat to global health, causing annual epidemics and occasional pandemics with substantial morbidity and mortality. Despite the availability of vaccines and antiviral therapies, the development of novel preventive and therapeutic strategies remains a critical research focus.
Di Wang   +7 more
wiley   +1 more source

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