Results 21 to 30 of about 51,260 (112)

Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease

Acta Neuropathologica
Parkinson’s disease (PD) starts at the molecular and cellular level long before motor symptoms appear, yet there are no early-stage molecular biomarkers for diagnosis, prognosis prediction, or monitoring therapeutic response.
J. Rutledge, B. Lehallier, P. Zarifkar, P. M. Losada, Marian Shahid-Besanti, D. Western, P. Gorijala, S. Ryman, Maya V Yutsis, Gayle K. Deutsch, E. Mormino, Alexandra N. Trelle, Anthony D. Wagner, Geoffrey A. Kerchner, Lu Tian, C. Cruchaga, Victor W. Henderson, T. Montine, P. Borghammer, Tony Wyss-Coray, K. Poston   +20 more
semanticscholar   +1 more source

UEG Week 2023 Moderated Posters

, 2023
United European Gastroenterology Journal, Volume 11, Issue S8, Page 201-534, October 2023.
wiley   +1 more source

Pivotal roles of Kupffer cells in the progression and regression of DDC-induced chronic cholangiopathy

Scientific Reports, 2018
Kupffer cells (KCs) are key players in maintaining tissue homeostasis and are involved in various liver diseases. However, the roles of KCs in the pathogenesis of cholangiopathy are largely unknown.
Leila Jemail, Masashi Miyao, H. Kotani, C. Kawai, Hirozo Minami, H. Abiru, Keiji Tamaki   +6 more
semanticscholar   +1 more source

Protective effect of green perilla-derived chalcone derivative DDC on amyloid β protein-induced neurotoxicity in primary cortical neurons.

Biological and Pharmaceutical Bulletin, 2019
Amyloid β protein (Aβ) causes neurotoxicity and cognitive impairment in Alzheimer's disease (AD). Oxidative stress is closely related to the pathogenesis of AD.
M. Iwasaki, Naotaka Izuo, Yasuhiko Izumi, Yuki Takada‐Takatori, A. Akaike, T. Kume   +5 more
semanticscholar   +1 more source

Abstracts

, 2023
Molecular Oncology, Volume 17, Issue S1, Page 1-597, June 2023.
wiley   +1 more source

The SGLT2 inhibitor empagliflozin in patients hospitalized for acute heart failure: a multinational randomized trial

Nature Network Boston, 2022
The sodium–glucose cotransporter 2 inhibitor empagliflozin reduces the risk of cardiovascular death or heart failure hospitalization in patients with chronic heart failure, but whether empagliflozin also improves clinical outcomes when initiated in ...
A. Voors, C. Angermann, J. Teerlink, S. Collins, M. Kosiborod, J. Biegus, J. Ferreira, M. Nassif, M. Psotka, J. Tromp, C. Borleffs, Changsheng Ma, J. Comín-Colet, M. Fu, S. Janssens, R. Kiss, R. Mentz, Y. Sakata, H. Schirmer, M. Schou, P. Schulze, L. Špinarová, M. Volterrani, J. Wranicz, U. Zeymer, S. Zieroth, M. Brueckmann, Jon Blatchford, A. Salsali, P. Ponikowski   +29 more
semanticscholar   +1 more source

USP38, FREM3, SDC1, DDC, and LOC727982 Gene Polymorphisms and Differential Susceptibility to Severe Malaria in Tanzania

Journal of Infectious Diseases, 2015
Populations exposed to Plasmodium falciparum infection develop genetic mechanisms of protection against severe malarial disease. Despite decades of genetic epidemiological research, the sickle cell trait (HbAS) sickle cell polymorphism, ABO blood group ...
A. Manjurano, N. Sepúlveda, Behzad Nadjm, G. Mtove, Hannah Wangai, C. Maxwell, R. Olomi, Hugh Reyburn, C. Drakeley, E. Riley, T. Clark   +10 more
semanticscholar   +1 more source

Ink‐Extrusion 3D Printing and Silicide Coating of HfNbTaTiZr Refractory High‐Entropy Alloy for Extreme Temperature Applications

Advanced Science, Volume 11, Issue 17, May 8, 2024.
This work demonstrates that an oxygen‐sensitive refractory high‐entropy alloy (RHEA) can achieve architecture freedom and good oxidation resistance by a series of simple processing steps: i) 3D ink‐extrusion printing, ii) interdiffusion‐sintering, and iii) silicide coating.
Dingchang Zhang, Ya‐Chu Hsu, David C. Dunand   +2 more
wiley   +1 more source

Annual banned‐substance review 16th edition—Analytical approaches in human sports drug testing 2022/2023

Drug Testing and Analysis, Volume 16, Issue 1, Page 5-29, January 2024.
Abstract In this 16th edition of the annual banned‐substance review on analytical approaches in human sports drug testing, literature on recent developments in this particular section of global anti‐doping efforts that was published between October 2022 and September 2023 is summarized and discussed.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Increased leukotoxin production: Characterization of 100 base pairs within the 530 base pair leukotoxin promoter region of Aggregatibacter actinomycetemcomitans

Scientific Reports, 2017
Aggregatibacter actinomycetemcomitans leukotoxin (LtxA) is a major virulence factor that kills leukocytes permitting it’s escape from host immune surveillance. A. actinomycetemcomitans strains can produce high or low levels of toxin.
V. Sampathkumar, S. Velusamy, Dipti Godboley, D. Fine   +3 more
semanticscholar   +1 more source