Results 11 to 20 of about 547 (67)

Bird's eye view of natural products for the development of new anti-HIV agents: Understanding from a therapeutic viewpoint. [PDF]

open access: yesAnimal Model Exp Med
Development of pharmaceutical drugs to cure HIV is crucial due to the current widespread epidemic. Nucleosides are the most effective anti‐HIV drugs, but their high toxicity and drug resistance limit their use. This review focuses on potential natural medicinal products for treating and managing HIV and AIDS.
Al Amin M   +12 more
europepmc   +2 more sources

Towards a Sustainable Future: Addressing Climate Change and Promoting Sustainable Development

open access: yesSustainable Development, Volume 34, Issue S1, Page 226-247, January 2026.
ABSTRACT This study aims to analyze policy research and global agreements on the decarbonization of economic development. Climate change and economic development are separate and equal, and strategies should separate responsibility from action. This will be required beyond the Kyoto and Paris agreements.
Woo‐Sik Sohn
wiley   +1 more source

Effect of High‐Pressure Processing Operating Parameters on Microbial Inactivation and Bioactive Protein Preservation in Bovine Milk: A Systematic Review

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT In the U.S., bovine milk is processed using thermal pasteurization to ensure microbial safety. However, this process alters the structure of heat‐sensitive bioactive proteins associated with the functional benefits of raw milk, including antimicrobial, immunomodulatory, and antioxidant proteins.
Rudy Sykora   +5 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +31 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +28 more
wiley   +1 more source

Metformin and insulin exacerbate one‐carbon metabolism deficits in pregnant growth restricted rats and impacts the placenta, fetal liver and pancreas

open access: yesThe Journal of Physiology, Volume 603, Issue 19, Page 5751-5775, October 1, 2025.
Abstract figure legend Uteroplacental insufficiency (growth restricted) or sham (Control) surgery was performed on embryonic day (E)18 in Wistar–Kyoto rats. Female F1 offspring were mated and restricted dams received daily metformin, insulin or vehicle from E13.
Dayna A. Zimmerman   +11 more
wiley   +1 more source

Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications

open access: yesMedComm, Volume 6, Issue 9, September 2025.
Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen   +4 more
wiley   +1 more source

Examining the ‘gendered’ places and spaces of UK doctoral education using multilevel modelling

open access: yesTransactions of the Institute of British Geographers, Volume 50, Issue 3, September 2025.
Short Abstract Research on gender in higher education frequently focuses on either micro‐ or macro‐scale factors, such as power relations and working practices, or disciplinary norms and the educational ‘pipeline’. As a result, the connecting meso‐scale of ‘place’—embodied in the department and institution—is often missing both conceptually and ...
Laura Harriet Sheppard   +2 more
wiley   +1 more source

Co–Fe–Ni‐Based High‐Entropy Superalloys with γ/γ′ Microstructure

open access: yesAdvanced Engineering Materials, Volume 27, Issue 7, April 2025.
Six high‐entropy superalloys are designed and evaluated for high‐temperature phase stability. In the results of this study, future alloy design and computational databases are informed for coherent precipitate‐strengthened alloys. The most promising alloy of this study has completely equiatomic γ and γ’ formers, demonstrating that a new class of high ...
Brandon Ohl, Davin Yoo, David C. Dunand
wiley   +1 more source

Ink Casting and 3D‐Extrusion Printing of Yb14MnSb11 for High‐Temperature Thermoelectric Material

open access: yesAdvanced Functional Materials, Volume 35, Issue 8, February 19, 2025.
3D‐structured Yb14MnSb11, a p‐type thermoelectric material exhibiting high values of Figure of Merit (zT1) until 1000 °C, is fabricated using ink‐extrusion printing and pressureless reactive sintering, achieving a high phase purity (83–94%) and a low porosity (82% relative density).
Ming Chen   +5 more
wiley   +1 more source

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