Results 11 to 20 of about 357 (67)
Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets. [PDF]
MedComm (2020)Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Li G +13 more
europepmc +2 more sources
Guidelines for mouse and human DC functional assays
European Journal of Immunology, Volume 53, Issue 12, December 2023., 2023 Conventional DC (cDC) represent a heterogenous family of professional antigen‐presenting cells. Basic functions common to all tissue‐resident cDC include antigen uptake, lymph node migration, and naive T cell priming to induce appropriate effector and regulatory T cell responses.
Björn E. Clausen +45 more
wiley +1 more source
The FASEB Journal, Volume 37, Issue 12, December 2023., 2023 Olfactory dysfunction is one of the most prevalent symptoms of Parkinson's disease preceding clinical onset by up to a decade. However, PD models focus mainly on motor symptoms and nigrostriatal degeneration. Here, we characterize cultured olfactory bulb organotypic slices and cells and explore the effect of DOPAL, a metabolite of dopamine.
Enrico Bagnoli +6 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2023/24: Enzymes
British Journal of Pharmacology, Volume 180, Issue S2, Page S289-S373, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander +28 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2023/24: Transporters
British Journal of Pharmacology, Volume 180, Issue S2, Page S374-S469, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander +27 more
wiley +1 more source
Clinical and Translational Medicine, Volume 12, Issue 9, September 2022., 2022 The first mass spectrometry–based proteomic analysis on small‐cell lung cancer (SCLC) cell lines, reporting unique proteomic profiles of its proposed molecular subtypes. SCLC subgroups detected by proteomics are consistent with mRNA‐based subtypes.
Beáta Szeitz +20 more
wiley +1 more source
Geochemistry, Geophysics, Geosystems, Volume 23, Issue 9, September 2022., 2022 Abstract Double seismic zones (DSZs), parallel planes of intermediate‐depth earthquakes inside oceanic slabs, have been observed in a number of subduction zones and may be a ubiquitous feature of downgoing oceanic plates. Focal mechanism observations from DSZ earthquakes sample the intraslab stress field at two distinct depth levels within the ...
C. Sippl +3 more
wiley +1 more source
Journal of Comparative Neurology, Volume 530, Issue 11, Page 1773-1949, August 2022., 2022 By using a genetically modified mouse model and viral tracing approaches, we mapped both the anterograde and the retrograde projections of a subpopulation of neurons in the anterior paraventricular thalamic nucleus, molecularly defined by the expression of glucokinase (GckaPVT).
Sevasti Gaspari +4 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Transporters
British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source