Results 31 to 40 of about 1,495,680 (149)
Cell Proliferation, EarlyView.Song et al. developed an mGM‐CSF‐loaded, liver cancer cell‐based vaccine that potently activated dendritic cells and elicited tumour‐specific T cell responses. Mechanistically, radiation‐induced oxidative damage to mitochondrial DNA in cancer cells triggers the cGAS‐STING pathway in DCs, which synergizes with mGM‐CSF‐driven JAK2‐STAT3 signalling to ...
Zhiruo Song +15 more
wiley +1 more source
The FEBS Journal, EarlyView.MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz +13 more
wiley +1 more source
Annual Report of the IPCC DDC at WDCC for 2016
, 2017 This report provides statistics on the data download from the Reference Data Archive for climate model output hosted at the IPCC DDC at WDCC/DKRZ (http://ipcc.wdc-climate.de) for ...
Lautenschlager, Michael +1 more
core +1 more source
HIV Medicine, EarlyView.Abstract Introduction Antiretroviral therapy (ART) for people living with HIV has led to dramatically reduced mortality and improved life expectancy. This achievement is accompanied by a higher risk for metabolic and other non‐communicable diseases. The role and contribution of various ART regimens to adverse metabolic outcomes are not fully understood.
Melani Ratih Mahanani +7 more
wiley +1 more source
2016 Usage Report for the IPCC DDC -‐ Supplementary
, 2017 This report presents annual statistics for the geographical distribution of user sessions for the IPCC-DDC web site www.ipcc‐data.org. The IPCC-DDC usage information is presented as a series of maps with corresponding data tables. Note that data for the
Pascoe, Charlotte
core +1 more source
Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy
Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva +5 more
wiley +1 more source
, 2017 Presentation introducing the Centre for Environmental Data Analysis and its role in running a component of the IPCC Data Distribution CentrePresented at the first IPCC DDC AR6 workshop, DKRZ, Hamburg, 19th Sept ...
Juckes, Martin (5375818), Juckes, Martin
core +1 more source
Vaccine Research, 2017 Introduction: Hepatitis C virus (HCV) is one of the most serious causes of cirrhosis, liver cancer and ultimately death, worldwide. The new direct-acting drugs are not accessible for many patients around the world and progress toward new therapeutic and ...
S Hekmat +10 more
doaj
Optimization of Diffusion MRI With Consideration of the Signal Decay in Biological Tissues
Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 460-468, July 2026.ABSTRACT Purpose Devising methodology to characterize and optimize acquisition schemes for biological tissues, such as the prostate, that produce model‐based synthetic diffusion‐weighted images and derived model parameters with predictable SNR improvement. Methods The averaging effect (AE) in synthetic diffusion‐weighted images obtained through fitting
Stefan Kuczera, Stephan E. Maier
wiley +1 more source
Brain Pathology, Volume 36, Issue 4, July 2026.A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña +20 more
wiley +1 more source