Results 21 to 30 of about 1,495,680 (149)

2018 Usage Report for the IPCC DDC at CEDA [PDF]

open access: yes, 2019
This report provides details of how the DDC web site, ipcc-data.org, was used in the 12 months from January 1st 2018 to December 31st 2018. The information presented here is generated using the Google Analytics service; providing a range of different ...
Pascoe, Charlotte   +1 more
core   +1 more source

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

open access: yesAdvanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar   +10 more
wiley   +1 more source

WGI DDC workshop presentation

open access: yes, 2017
<p>This presentation shows the outline of the Working Group I contribution to the AR6, showing the internal and cross-WG connections, to set the scene for the data needs of the WGI report.
Pirani, Anna (6418049)   +3 more
core   +1 more source

Nucleoside supplements as treatments for mitochondrial DNA depletion syndrome

open access: yesFrontiers in Cell and Developmental Biology
Introduction: In mitochondrial DNA (mtDNA) depletion syndrome (MDS), patients cannot maintain sufficient mtDNA for their energy needs. MDS presentations range from infantile encephalopathy with hepatopathy (Alpers syndrome) to adult chronic progressive ...
Eszter Dombi   +9 more
doaj   +1 more source

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

open access: yesAdvanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao   +7 more
wiley   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska   +4 more
wiley   +1 more source

Annual Report of the IPCC DDC at WDCC for 2014

open access: yes, 2015
This report provides statistics on the data download from the Reference Data Archive for climate model output hosted at the IPCC DDC at WDCC/DKRZ (http://ipcc.wdc-climate.de) for ...
Lautenschlager, Michael   +2 more
core   +1 more source

Data‐Driven Insights into Hyperkinetic Disorders in Neurodevelopmental Syndromes and Epileptic Encephalopathies

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Childhood‐onset hyperkinetic movement disorders occur in a range of genetic conditions. Recently, there has been an increase in recognition of hyperkinetic movement disorders, mainly dystonia, chorea and dyskinesia, with monogenic conditions associated with neurodevelopmental delay (NDD) and also with developmental and epileptic ...
Hugo Morales‐Briceño   +6 more
wiley   +1 more source

Annual Report of the IPCC DDC at WDCC for 2015

open access: yes, 2016
This report provides statistics on the data download from the Reference Data Archive for climate model output hosted at the IPCC DDC at WDCC/DKRZ (http://ipcc.wdc-climate.de) for ...
Lautenschlager, Michael   +1 more
core   +1 more source

Consistent Choice of Prey Source Habitat Across Diverse Landscapes by a Selective Insectivorous Bat

open access: yesIntegrative Zoology, EarlyView.
After analyzing the diet of the greater horseshoe bats in three distinct colonies, we identified significant spatial and temporal differences, particularly noting a stronger reliance on riparian habitats in Mediterranean areas. The species exhibits great ecological adaptability with strong plasticity in prey source habitats, shifting preferences among ...
Miren Aldasoro   +7 more
wiley   +1 more source

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