Results 1 to 10 of about 1,495,680 (149)

Cyclodextrin Diethyldithiocarbamate Copper II Inclusion Complexes: A Promising Chemotherapeutic Delivery System against Chemoresistant Triple Negative Breast Cancer Cell Lines

Pharmaceutics, 2021
Diethyldithiocarbamate Copper II (DDC-Cu) has shown potent anticancer activity against a wide range of cancer cells, but further investigations are hindered by its practical insolubility in water.
Ammar Said Suliman, Mouhamad Khoder, Ibrahim Tolaymat, Matt Webster, Raid G. Alany, Weiguang Wang, Abdelbary Elhissi, Mohammad Najlah   +7 more
doaj   +1 more source

3D Spheroids of Human Primary Urine-Derived Stem Cells in the Assessment of Drug-Induced Mitochondrial Toxicity

Pharmaceutics, 2022
Mitochondrial toxicity (Mito-Tox) risk has increased due to the administration of several classes of drugs, particularly some life-long antiretroviral drugs for HIV+ individuals.
Huifen Ding, Kalyani Jambunathan, Guochun Jiang, David M. Margolis, Iris Leng, Michael Ihnat, Jian-Xing Ma, Jon Mirsalis, Yuanyuan Zhang   +8 more
doaj   +1 more source

Short-term effects in canopy gap area on the recovery of compacted soil caused by forest harvesting in old-growth Oriental beech (Fagus orientalis Lipsky) stands

iForest - Biogeosciences and Forestry, 2021
Natural treefall gaps have a substantial role in maintaining soil and plant diversity in old-growth forests. However, the amount of information on the effects of gaps on the recovery of physical and chemical properties of compacted soils is scarce.
Jourgholami M, Feghhi J, Tavankar F, Latterini F, Venanzi R, Picchio R   +5 more
doaj   +1 more source

Disparity in the detection of chromosome 15 centromere in patients of African ancestry with a plasma cell neoplasm

Genetics in Medicine Open, 2023
Purpose: Fluorescence in situ hybridization (FISH) is the current gold standard assay that provides information related to risk stratification and therapeutic selection for individuals with plasma cell neoplasms.
Alaa Koleilat, Hongwei Tang, Neeraj Sharma, Huihuang Yan, Shulan Tian, James Smadbeck, Suganti Shivaram, Reid Meyer, Kathryn Pearce, Michael Baird, Cinthya J. Zepeda-Mendoza, Xinjie Xu, Patricia T. Greipp, Jess F. Peterson, Rhett P. Ketterling, P. Leif Bergsagel, Celine Vachon, S. Vincent Rajkumar, Shaji Kumar, Yan W. Asmann, Eran Elhaik, Linda B. Baughn   +21 more
doaj   +1 more source

Low-Voltage Gate-Leakage-Based Timer Using an Amplifier-Less Replica-Bias Switching Technique in 55-nm DDC CMOS

IEEE Open Journal of Circuits and Systems, 2020
Energy-efficient timer circuits are required in numerous applications for periodic operations, such as performing measurements and communicating data.
Atsuki Kobayashi, Kiichi Niitsu
doaj   +1 more source

Non-mono-exponential diffusion models for assessing early response of liver metastases to chemotherapy in colorectal Cancer

Cancer Imaging, 2019
Background Preoperative chemotherapy is becoming standard therapy for liver metastasis from colorectal cancer, so early assessment of treatment response is crucial to make a reasonable therapeutic regimen and avoid overtreatment, especially for patients ...
Yang Zhou, Hong-Xia Zhang, Xiu-Shi Zhang, Yun-Feng Sun, Kuang-Bang He, Xi-Qiao Sang, Yue-Min Zhu, Zi-Xiang Kuai   +7 more
doaj   +1 more source

Efficient Elimination of mtDNA from Mammalian Cells with 2′,3′-Dideoxycytidine

DNA
Mammalian cell lines devoid of mitochondrial DNA (mtDNA) are indispensable in studies aimed at elucidating the contribution of mtDNA to various cellular processes or interactions between nuclear and mitochondrial genomes. However, the repertoire of tools
Natalya Kozhukhar, Mikhail F. Alexeyev
doaj   +1 more source

Grading of clear cell renal cell carcinoma by using monoexponential, biexponential, and stretched exponential diffusion-weighted MR imaging

Frontiers in Oncology
ObjectivesTo evaluate the diagnostic accuracy of monoexponential, biexponential and stretched-exponential diffusion-weighted imaging (DWI) models in the grading of clear cell renal cell carcinoma (ccRCC).Materials and MethodsFifty-one patients with ...
Wenhui Wang, Lingdian Wang, Jing Zhou, Taiyuan Liu, Yan Bai, Meiyun Wang, Meiyun Wang   +6 more
doaj   +1 more source

A Practical Multimodal Fusion System With Uncertainty Modeling for Robust Visual and Affective Applications

IEEE Access
Multimodal fusion models are widely applied in practical tasks such as image classification and sentiment analysis. However, real-world data often contain noisy or imbalanced modality inputs, significantly affecting the performance of traditional fusion ...
Lei Pan, Xingyu Han, Xiaoming Liu, Yang Liu   +3 more
doaj   +1 more source

Traction Force Microscopy for Viscoelastic Substrates: A Semi‐Analytical Method

Advanced Science, EarlyView.
A semi‐analytical viscoelastic traction force microscopy framework is introduced for quantifying time‐resolved cell tractions on flat finite‐thickness substrates. The method generalizes elastic traction force microscopy to Generalized Maxwell materials, identifies when elastic approximations remain valid and, when they do not, shows that inferred ...
Adrià Villacrosa‐Ribas, Daniëlle C. A. Duffhues, Pim van den Bersselaar, Sarah Pragnere, Bart G. W. Groenen, Mariana Azevedo Gonzalez Oliva, Giuseppe Ciccone, Manuel Salmeron‐Sanchez, Carlijn V. C. Bouten, Jose J. Muñoz, Vito Conte   +10 more
wiley   +1 more source