Results 31 to 40 of about 180,404 (254)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Relato de caso autóctone de leishmaniose visceral canina na zona sul do município do Rio de Janeiro Report on an autochthonous case of canine visceral leishmaniasis in the southern zone of the municipality of Rio de Janeiro

Revista da Sociedade Brasileira de Medicina Tropical, 2010
O Brasil enfrenta uma expansão e urbanização da leishmaniose visceral americana com casos humanos e caninos em várias cidades de grande porte. O presente relato descreve um caso de leishmaniose visceral canina autóctone em uma área não endêmica no ...
Fabiano Borges Figueiredo, Carlos José de Lima Barbosa Filho, Edvar Yuri Pacheco Schubach, Sandro Antonio Pereira, Lílian Dias Nascimento, Maria de Fátima Madeira   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

2-hydroxyethyl methacrylate composite - polypropylene mesh for preventing peritoneal adhesions in female dogs Compósito 2-hidroxietil dimetacrilato-tela de polipropileno para prevenção de aderências peritoneais em cadelas

Acta Cirúrgica Brasileira, 2010
PURPOSE: To evaluate whether the lining facing the visceral side of polypropylene mesh made with 2-hydroxyethyl methacrylate (p(HEMA)) hydrogel could avoid peritoneal adhesion in female dogs.
Marcelo Seixo de Brito e Silva, Renato Miranda de Melo, Liliana Borges de Menezes, Sonia Maria Malmonge, Leandro Guimarães Franco, Neusa Margarida Paulo   +5 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

El nihilismo y las nuevas formas de la imagen tardomoderna / Nihilism and the new forms of the late-modern image

Bajo Palabra, 2016
Trad. de Valerio RoccoNos encontramos ante una revolución de la experiencia estética que puede denominarse “explosión de la imagen”. La imagen genera su propio médium y éste vuelve perceptible la imagen, la vuelve perceptible en cuanto imagen, evitando ...
Federico Vercellone
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Identificação de Faces em Imagens Bidimensionais

Revista Eletrônica TECCEN, 2009
O objetivo deste trabalho é a realização de um estudo a respeito das técnicas de Biometria mais conhecidas e pesquisadas atualmente, suas aplicações e características, como confiabilidade e eficiência. Além disso, apresenta-se também a sua maturidade em âmbito internacional.
David de S. A. Pereiral, José Antônio R. de Rapozo, Júlio César da Silva, Eugênio da Silva   +3 more
openaire   +4 more sources