Results 91 to 100 of about 1,286,932 (258)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Implementing tokenization in clinical research to expand real-world insights
Frontiers in Drug Safety and RegulationInterest in leveraging real-world data (RWD) to support clinical research is increasing, including studies to further characterize safety and effectiveness of new treatments.
Chelsea Walters +6 more
doaj +1 more source
Digital speech algorithms for speaker de-identification
2014 5th IEEE Conference on Cognitive Infocommunications (CogInfoCom), 2014 4 ...
Stefano Marinozzi, Marcos Faúndez-Zanuy
openaire +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Face De-Identification Using Convolutional Neural Network (CNN) Models for Visual-Copy Detection
Applied SciencesThe proliferation of media-sharing platforms has led to issues with illegally edited content and the distribution of pornography. To protect personal information, de-identification technologies are being developed to prevent facial identification ...
Jinha Song, Juntae Kim, Jongho Nang
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Journal of eScience LibrarianshipRespect for research participant rights is a key aspect for consideration when creating and utilizing interoperable data. From that perspective, requirements for sharing research data often call for the data to be de-identified, i.e., the removal of all ...
Zixin Nie
doaj +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
NLP-based removal of personally identifiable information from Hungarian electronic health records
Frontiers in Artificial IntelligenceIntroductionElectronic health records (EHR) in text format serve as crucial resources for data-driven medical research. To safeguard patient confidentiality, under the General Data Protection Regulation (GDPR), strict measures are required to ensure ...
András Berzi +5 more
doaj +1 more source