Results 101 to 110 of about 1,286,932 (258)

Improving Presentation Attack Detection in Dynamic Handwritten Signature Biometrics

IEEE Access, 2017
Handwritten signature recognition is a biometric mode that has started to be deployed. Therefore, it is necessary to analyze the robustness of the recognition process against presentation attacks, to find its vulnerabilities.
Raul Sanchez-Reillo, Helga C. Quiros-Sandoval, Ines Goicoechea-Telleria, Wendy Ponce-Hernandez   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Deep Learning Framework for Advanced De-Identification of Protected Health Information

Future Internet
Electronic health records (EHRs) are widely used in healthcare institutions worldwide, containing vast amounts of unstructured textual data. However, the sensitive nature of Protected Health Information (PHI) embedded within these records presents ...
Ahmad Aloqaily, Emad E. Abdallah, Rahaf Al-Zyoud, Esraa Abu Elsoud, Malak Al-Hassan, Alaa E. Abdallah   +5 more
doaj   +1 more source

Face De-Identification for Privacy Protection

, 2019
The ability to record, store and analyse images of faces economically, rapidly and on a vast scale brings people’s attention to privacy. The current privacy protection approaches for face images are mainly through masking, blurring or black-out which, however, removes data utilities along with the identifying information.
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Medical Manifestation-Aware De-Identification

Proceedings of the AAAI Conference on Artificial Intelligence
Face de-identification (DeID) has been widely studied for common scenes, but remains under-researched for medical scenes, mostly due to the lack of large-scale patient face datasets. In this paper, we release MeMa, consisting of over 40,000 photo-realistic patient faces. MeMa is re-generated from massive real patient photos. By carefully modulating the
Yuan Tian 0017, Shuo Wang, Guangtao Zhai
openaire   +2 more sources