Results 31 to 40 of about 2,481,224 (301)

Genomic landscapes and clonality of de novo AML [PDF]

, 2013
No abstract ...
Brewin, John, Chevassut, Timothy, Horne, Gillian   +2 more
core   +1 more source

Benthic estuarine communities' contribution to bioturbation under the experimental effect of marine heatwaves

Scientific Reports, 2021
Marine heatwaves are increasing worldwide, with several negative impacts on biological communities and ecosystems. This 24-day study tested heatwaves' effect with distinct duration and recovery periods on benthic estuarine communities' diversity and ...
M. Dolbeth, O. Babe, D. A. Costa, A. P. Mucha, P. G. Cardoso, F. Arenas   +5 more
doaj   +1 more source

How much of the variation in the mutation rate along the human genome can be explained? [PDF]

, 2014
It has been claimed recently that it may be possible to predict the rate of de novo mutation of each site in the human genome with a high degree of accuracy [Michaelson et al. (2012), Cell 151: 143121442]. We show that this claim is unwarranted.
Eyre-Walker, Adam, Eyre-Walker, Ying Chen   +1 more
core   +1 more source

Colorteca da associação de pais e amigos dos excepcionais de Mundo Novo, Mato Grosso do Sul

RealizAção, 2018
A educação em solos se bem aplicada pode ser um instrumento valioso e de grande uso para promover a conscientização ambiental ampliando assim a percepção do solo como componente essencial do meio ambiente. O presente trabalho teve como objetivo construir
Beatriz dos Anjos Generoso, Gledson Martins, João Carlos Gonçalves Vilhalba, Jean Sérgio Rosset, Carlos Antônio Molina Azevedo   +4 more
doaj   +1 more source

ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways. [PDF]

, 2017
Leukemia cells rely on two nucleotide biosynthetic pathways, de novo and salvage, to produce dNTPs for DNA replication. Here, using metabolomic, proteomic, and phosphoproteomic approaches, we show that inhibition of the replication stress sensing kinase ...
Abt, Evan R, Braas, Daniel, Capri, Joseph R, Cheng, Chloe M, Czernin, Johannes, Donahue, Timothy R, Faull, Kym F, Herschman, Harvey R, Kim, Woosuk, Kornblum, Harley I, Le, Thuc M, Merkurjev, Daria, Nikanjam, Mina, Poddar, Soumya, Radu, Caius G, Ribas, Antoni, Rix, Peter, Uong, Nhu T, Wei, Liu, Whitelegge, Julian, Zaretsky, Jesse   +20 more
core   +2 more sources

Universidade Pública e Inclusão Social: As Cotas para Autodeclarados Negros na Universidade Federal do Rio Grande do Sul

Cadernos Gestão Pública e Cidadania, 2011
A implementação de cotas raciais nas universidades públicas brasileiras é um processo recente e ainda em avaliação. Com o objetivo de analisar como essa experiência está ocorrendo, especialmente em sua efetividade enquanto ação inclusiva, realizou-se ...
Maria Cristina Lunardi Kern, Denise Macedo Ziliotto   +1 more
doaj   +1 more source

Grad-div stabilization for the time-dependent Boussinesq equations with inf-sup stable finite elements [PDF]

, 2019
In this paper we consider inf-sup stable nite element discretizations of the evolutionary Boussinesq equations with a grad-div type stabilization. We prove error bounds for the method with constants independent on the Rayleigh numbersMINECO grant ...
Frutos Baraja, Francisco Javier de, García Archilla, Juan Bosco, Novo, Julia   +2 more
core   +1 more source

De Novo Genes

Annual Review of Genetics
Although the majority of annotated new genes in a given genome appear to have arisen from duplication-related mechanisms, recent studies have shown that genes can also originate de novo from ancestrally nongenic sequences. Investigating de novo–originated genes offers rich opportunities to understand the origin and functions of new genes, their ...
Li, Zhao, Nicolas, Svetec, David J, Begun   +2 more
openaire   +2 more sources

The Tradescantia pallida var. purpurea active bioassay for water monitoring: evaluating and comparing methodological conditions

Revista Ambiente & Água, 2014
Tradescantia pallida var. purpurea cuttings with flower buds are utilized in bioassays to diagnose genotoxic effects of water. The literature describes different substances used to adapt and recover the cuttings before and after exposure to water samples
Mara Betânia Brizola Cassanego, Gustavo Marques da Costa, Márcio Hisayuki Sasamori, Delio Endres Júnior, Camila Tamires Petry, Annette Droste   +5 more
doaj   +1 more source

De novo ChIP-seq analysis [PDF]

Genome Biology, 2015
Methods for the analysis of chromatin immunoprecipitation sequencing (ChIP-seq) data start by aligning the short reads to a reference genome. While often successful, they are not appropriate for cases where a reference genome is not available. Here we develop methods for de novo analysis of ChIP-seq data.
He, Xin, Cicek, A. Ercument, Wang, Yuhao, Schulz, Marcel H., Le, Hai-Son, Bar-Joseph, Ziv   +5 more
openaire   +5 more sources