De novo assembly and annotation of the singing mouse genome. [PDF]
Smith SK +9 more
europepmc +1 more source
Abstract Premise As the sister clade to angiosperms, extant gymnosperms are crucial for reconstructing ancestral gene regulatory networks in seed plants. This highlights the need for model systems representing each of their distinct lineages. However, tools to quickly and effectively investigate gene function in gymnosperms are still limited due to the
Anthony G. K. Garcia +4 more
wiley +1 more source
Hybridization capture long-read sequencing and de novo assembly of homologous haplotypes: a comprehensive hemophilia test. [PDF]
Liu B +11 more
europepmc +1 more source
A cost‐effective DNA extraction protocol for long‐read sequencing in non‐model plants
Abstract Premise Third‐generation sequencing has revolutionized genomics, enabling in‐depth analysis of genome sequence, structure, and epigenetic features. Yet, extracting high‐quality DNA for long‐read sequencing remains a bottleneck—particularly in non‐model plants, such as mature trees growing in natural environments, which often contain abundant ...
Sofia Gaischuk +6 more
wiley +1 more source
De novo assembly and comparative analysis of the mitochondrial genome of Reynoutria japonica. [PDF]
Chen J +5 more
europepmc +1 more source
Twist Engineering of Hybrid 2D van der Waals‐Transition Metal Oxide Membranes
The integration of transition metal oxide membranes with 2D van der Waals materials offers exciting opportunities to study new interfacial phenomena. These interactions can create complex moiré patterns that change the materials' properties. Understanding these interactions, influenced by symmetry and distortion, poses significant challenges and ...
Mar Garcia Hernandez +4 more
wiley +1 more source
Resequencing and De Novo Assembly of Leishmania (Viannia) guyanensis from Amazon Region: Genome Assessment, Phylogenetic Insights and Therapeutic Targets. [PDF]
Costa LGA +6 more
europepmc +1 more source
Self-indexing for de novo assembly
For at least three decades computer science approaches have proved to be of utmost importance for extrapolating knowledge from biological data. Indeed, the amount of data produced by sequencing technologies has increased more than exponentially, outpacing Moore's law and making automatic analysis the only viable option.
openaire +1 more source
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
A de novo assembly based fusion gene detection concept based on DNA-seq data of 100 Ewing sarcoma cases. [PDF]
Zhao X, Hotfilder M, Korsching E.
europepmc +1 more source

