Results 121 to 130 of about 61,982,689 (238)

Hydrogen atom in de Sitter spaces

open access: yes, 2014
17 pages, Report to International Conference and Workshop "Quanta and %Matter: Through Physics to Future Emerging Technologies. 22-26 September 2014.
Veko, O. V.   +4 more
openaire   +3 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Quantum theory in de-Sitter space [PDF]

open access: yesCommunications in Mathematical Physics, 1967
A general method for constructing fields in spaces with transitive group of transformations is presented. Quantum-theory of free fields with spin 0, 1/2, and the connection of spin and statistics in de-Sitter space of constant positive curvature are discussed.
openaire   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Schwinger current in de Sitter space*

open access: yesChinese Physics C
Abstract We study classical background electric fields and the Schwinger effect in de Sitter space. We show that a constant electric field in de Sitter requires the photon to have a tachyonic mass proportional to the Hubble scale.
Mar Bastero-Gil   +4 more
openaire   +2 more sources

Resummation of cosmological correlators and their UV-regularization

open access: yesJournal of High Energy Physics
Cosmological correlators are important observables in cosmology. They are often approximated by de Sitter space correlators. In this paper, we give a first precise diagrammatical computation of higher loop diagrams to all orders for a conformally coupled
Matthias Nowinski, Ivo Sachs
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

De Sitter space is sometimes not empty

open access: yesJournal of High Energy Physics
Multiple lines of evidence suggest that the Hilbert space of an isolated de Sitter universe is one dimensional but can appear larger when probed by a gravitating observer.
Vijay Balasubramanian   +2 more
doaj   +1 more source

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