Results 71 to 80 of about 61,982,689 (238)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Biharmonic Hypersurfaces in Pseudo-Riemannian Space Forms with at Most Two Distinct Principal Curvatures

open access: yesJournal of Function Spaces, 2020
In this paper, we show that biharmonic hypersurfaces with at most two distinct principal curvatures in pseudo-Riemannian space form Nsn+1c with constant sectional curvature c and index s have constant mean curvature.
Chao Yang, Jiancheng Liu
doaj   +1 more source

Small Schwarzschild de Sitter black holes, quantum extremal surfaces and islands

open access: yesJournal of High Energy Physics, 2022
We study 4-dimensional Schwarzschild de Sitter black holes in the regime where the black hole mass is small compared with the de Sitter scale. Then the de Sitter temperature is very low compared with that of the black hole and we study the black hole ...
Kaberi Goswami, K. Narayan
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

New coordinates for de Sitter space and de Sitter radiation

open access: yesPhysics Letters B, 2002
We introduce a simple coordinate system covering half of de Sitter space. The new coordinates have several attractive properties: the time direction is a Killing vector, the metric is smooth at the horizon, and constant-time slices are just flat Euclidean space. We demonstrate the usefulness of the coordinates by calculating the rate at which particles
openaire   +2 more sources

Exceptional scalar theories in de Sitter space

open access: yesJournal of High Energy Physics, 2022
The special galileon and Dirac-Born-Infeld (DBI) theories are effective field theories of a single scalar field that have many interesting properties in flat space. These theories can be extended to all maximally symmetric spaces, where their algebras of
James Bonifacio   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Confinement in anti-de Sitter space [PDF]

open access: yesJournal of High Energy Physics, 2013
29 pages, JHEP format.
Aharony, Ofer   +3 more
openaire   +2 more sources

On in-in correlators for spinning theories and their shadow formulation

open access: yesJournal of High Energy Physics
In-in correlators are the basic observables in cosmology and are traditionally computed using the Schwinger-Keldysh formalism. In this paper we revisit this formalism for photons, gluons, and gravitons coupled to scalars in four dimensional de Sitter ...
Chandramouli Chowdhury   +3 more
doaj   +1 more source

Spherical Symmetric Solutions for the Motion of Relativistic Membranes in the Schwarzschild-Anti de Sitter Space-Time

open access: yesJournal of Applied Mathematics, 2013
This paper concerns motion of relativistic membranes in the Schwarzschild-anti de Sitter space-time. We derive a nonlinear equation for relativistic membranes moving in the Schwarzschild-anti de Sitter space-time, discuss spherical symmetric solutions ...
Xiaoyan Li
doaj   +1 more source

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