Results 91 to 100 of about 60,692 (275)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Fusion of Optical Flow and Dead Reckoning Algorithms for UAV Navigation Without GPS [PDF]

open access: yesTransNav
The article presents an innovative navigation system for unmanned aerial vehicles (UAVs) operating in environments with limited or unavailable GPS signal.
Jakub Walczak   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Low-complexity online correction and calibration of pedestrian dead reckoning using map matching and GPS

open access: yesGeo-spatial Information Science, 2019
Dead Reckoning is a relative positioning scheme that is used to infer the change of position relative to a point of origin by measuring the traveled distance and orientation change. Pedestrian Dead Reckoning (PDR) applies this concept to walking persons.
Fabian Hölzke   +3 more
doaj   +1 more source

Context-Aware Statistical Dead Reckoning for Localization in IoT Scenarios. [PDF]

open access: yesSensors (Basel), 2023
Munoz-Rodriguez D   +2 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Dead reckoning

open access: yesLaw Text Culture, 1994
Four hundred years after Christopher Marlowe's death in a Deptford inn, stabbed through the right eye by one Ingram Frizer, two books continue searching for the reasons behind the murder: Charles Nicholl's The Reckoning and Anthony Burgess's A Dead Man in Deptford.
openaire   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

The Role of Trust and Interaction in GPS Related Accidents: A Human Factors Safety Assessment of the Global Positioning System (GPS) [PDF]

open access: yes, 2008
The Global Positioning System (GPS) uses a network of orbiting and geostationary satellites to calculate the position of a receiver over time. This technology has revolutionised a wide range of safety-critical industries and leisure applications ranging ...
Holloway, C.M., Johnson, C.W., Shea, C.
core  

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