MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 2015 In this paper, we describe about a study of dead-reckoning algorithm for mecanum wheel based mobile robot under various types of road surface. Because of mecanum wheel based mobile robot can move omni-direction by utilizing tire-road surface friction ...
上町 亮介
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
On Fusing Wireless Fingerprints with Pedestrian Dead Reckoning to Improve Indoor Localization Accuracy. [PDF]
Sensors (Basel)Fernando GC +4 more
europepmc +1 more source
An Improved Pedestrian Ttracking Method Based on Wi-Fi Fingerprinting and Pedestrian Dead Reckoning. [PDF]
Sensors (Basel), 2020 Feng B, Tang W, Guo G, Jia X.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Accurate Localization Method Combining Optimized Hybrid Neural Networks for Geomagnetic Localization with Multi-Feature Dead Reckoning. [PDF]
Sensors (Basel)Yan S +5 more
europepmc +1 more source
Design of a wireless assisted pedestrian dead reckoning system – the NavMote experience
, 2005 — In this paper, we combine inertial sensing and sensor network technology to create a pedestrian dead reckoning system. The core of the system is a lightweight sensor-andwireless-embedded device called NavMote that is carried by a pedestrian.
Panos J. Antsaklis +10 more
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Grid-Based Bayesian Filtering Methods for Pedestrian Dead Reckoning Indoor Positioning Using Smartphones. [PDF]
Sensors (Basel), 2020 Opiela M, Galčík F.
europepmc +1 more source