Results 161 to 170 of about 986,532 (289)

Agent‐Based Simulations of Lung Tumor Evolution Suggest That Ongoing Cell Competition Drives Realistic Clonal Expansions

Advanced Science, EarlyView.
Computational simulations of tumor evolution are increasingly used to infer the rules underlying cancer growth, with the goal of one day recommending tailored treatments. Here we show that the properties of lung cancer sequencing data are best replicated by a model which assumes that cells compete both to proliferate and survive. ABSTRACT Computational
Helena Coggan, James R. M. Black, Carlos Martínez‐Ruiz, Kristiana Grigoriadis, Jasmin Fisher, Nicholas McGranahan   +5 more
wiley   +1 more source

Origin and evolution of colorectal mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN). [PDF]

Endocr Relat Cancer
Morken S, Sorbye H, Deng W, Dogramaci HT, Venizelos A, Weber Vestermark L, Pfeiffer P, Kersten C, Perren A, Knappskog S.   +9 more
europepmc   +1 more source

Stochastic Entanglement of Deterministic Origami Tentacles For Robust Robotic Grasping

Advanced Science, EarlyView.
This study introduces an origami tentacle gripper to robustly grasp objects‐in air, underwater, and even in orbital space‐by exploiting a synergy between local, deterministic deformation programming and global, stochastic entanglements. A single origami tentacle can be designed to coil with a simple tendon pull.
Alec Boron, Bokun Zheng, Ziyang Zhou, Noel Naughton, Suyi Li   +4 more
wiley   +1 more source

Previous prescribed burns saved thousands of ancient sequoias during historically unprecedented wildfires. [PDF]

Nat Commun
Dixon DJ, Das AJ, Dong X, Latimer AM, Soderberg DN, Stephenson NL, Caprio AC, Jin Y.   +7 more
europepmc   +1 more source

View of dead trees at Anyox

Dead trees sparsely cover a rocky rugged hillside leading to higher treeless ...

core  

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

Advanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su, Xitao Wang, Musen Li, Guanhua Qin, Shunbo Hu, Tong‐Yi Zhang   +5 more
wiley   +1 more source

Dead trees in the virgin forest of Pečka

, 1999
This study treats dead trees and their remnants in the research areas of the Pe~ka virgin forest at a location of Abieti-Fagetum dinaricum. It covers four decaying stages: stump, mound, wood remnants, standing dead trees and their remnants. We first classify and describe the decaying stages, and define a manner of calculating their specific volume.
openaire   +1 more source

Improving carbon modeling in aspen-dominated forests: Lessons from CBM-CFS3 evaluation against long-term field data. [PDF]

Ecol Appl
Lau N, Sattler D, Michaelian M, Hararuk O.   +3 more
europepmc   +1 more source

Two men near dead trees

Two men stand in front of several dead trees. The edge of a reservoir is visible and granite outcrops can be seen in the distance. In folder: "Forests, Misc.

core  

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source