Results 41 to 50 of about 523 (266)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Frontiers in Energy ResearchModular Multilevel Converter (MMC) is widely used in applications such as High Voltage Direct Current (HVDC) transmission, AC/DC power conversion centers, and large-scale power quality management in electrical grids due to its highly modular structure ...
Yuan Cheng +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Sukkur IBA Journal of Emerging TechnologiesPermanent magnet synchronous motors (PMSMs) offer advantages such as high torque, power density, and energy efficiency, making them essential in power electronics, aerospace, and daily life.
Syed Abid Ali Shah Bukhari +3 more
doaj +1 more source
Science and Technology for Energy Transition, 2023 This article introduces an innovative approach called Adaptive Deadbeat Predictive Control (ADPC), specifically designed to regulate the operation of a Permanent Magnet Synchronous Motor (PMSM) within a solar-powered electric vehicle (SEV).
Ben Said-Romdhane Marwa +2 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
IEEE Access, 2022 To solve the problem that the conventional vector control system of permanent magnet synchronous motor is susceptible to motor parameters and load disturbances, a sliding mode predictive current control strategy of permanent magnet synchronous motor with
Limin Hou, Jianhua Ma, Wei Wang
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Digital implementation of three-phase rectifier with deadbeat controller
Eletrônica de Potência, 2002 A full digital control of a voltage source converter (VSC) rectifier is presented. The behavior of the AC and DC sides were modeled and used for the design of the AC current tracking controller and DC voltage regulator.
Alisson Dias Junqueira +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source