Results 41 to 50 of about 517 (267)

On the general solution of the state deadbeat control problem

open access: yesIEEE Transactions on Automatic Control, 1994
Summary: In this note, the state deadbeat control problem is considered. It is shown that, after appropriate change of basis of input and state space, the general solution of the state deadbeat control problem can be expressed completely by the rows of the powers of the system matrix.
ELDEM, V, SELBUZ, H
openaire   +3 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

An improved two-beat deadbeat synchronous predictive current control strategy for MMC based on Newton interpolation method

open access: yesFrontiers in Energy Research
Modular Multilevel Converter (MMC) is widely used in applications such as High Voltage Direct Current (HVDC) transmission, AC/DC power conversion centers, and large-scale power quality management in electrical grids due to its highly modular structure ...
Yuan Cheng   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Dual closed-loop vector PI control and deadbeat current control of permanent magnet synchronous motor

open access: yesSukkur IBA Journal of Emerging Technologies
Permanent magnet synchronous motors (PMSMs) offer advantages such as high torque, power density, and energy efficiency, making them essential in power electronics, aerospace, and daily life.
Syed Abid Ali Shah Bukhari   +3 more
doaj   +1 more source

Digital implementation of three-phase rectifier with deadbeat controller

open access: yesEletrônica de Potência, 2002
A full digital control of a voltage source converter (VSC) rectifier is presented. The behavior of the AC and DC sides were modeled and used for the design of the AC current tracking controller and DC voltage regulator.
Alisson Dias Junqueira   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Adaptive Deadbeat Predictive Control for PMSM-based solar-powered electric vehicles with enhanced stator resistance compensation

open access: yesScience and Technology for Energy Transition, 2023
This article introduces an innovative approach called Adaptive Deadbeat Predictive Control (ADPC), specifically designed to regulate the operation of a Permanent Magnet Synchronous Motor (PMSM) within a solar-powered electric vehicle (SEV).
Ben Said-Romdhane Marwa   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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