Results 201 to 210 of about 789,084 (305)

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li   +12 more
wiley   +1 more source

HiST: Histological Images Reconstruct Tumor Spatial Transcriptomics via MultiScale Fusion Deep Learning

open access: yesAdvanced Science, EarlyView.
HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li   +8 more
wiley   +1 more source

Single‐Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys

open access: yesAdvanced Science, EarlyView.
Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang   +10 more
wiley   +1 more source

HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration

open access: yesAdvanced Science, EarlyView.
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong   +14 more
wiley   +1 more source

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

open access: yesAdvanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu   +18 more
wiley   +1 more source

RQSM-Based Deadbeat Predictive Control for Dual-Active-Bridge Converters

IEEE Journal of Emerging and Selected Topics in Power Electronics
The voltage tracking performance of conventional finite-control-set model predictive control (FCS-MPC) is limited due to the FCS phase-shift-angle and parameter sensitivity in dual-active-bridge (DAB) converters. To address above issues, this paper proposes a robust-quasi-sliding-mode based deadbeat predictive control (RQSM-DPC), where the proposed ...
Zheng Yin   +7 more
openaire   +2 more sources

Adaptive Deadbeat Predictive Control for PMSM based Electric Vehicle

2022 IEEE International Conference on Electrical Sciences and Technologies in Maghreb (CISTEM), 2022
This article proposes an adaptive deadbeat predictive control (ADPC) for permanent-magnet synchronous motor (PMSM) included in a solar powered electric vehicle.
Marwa Ben Said-Romdhane   +2 more
openaire   +2 more sources

A Reconstructed Nearest Level Modulation Method With ABC Coordinate-Based Deadbeat Predictive Control for the Four-Level Single Flying Capacitor Converter

IEEE Journal of Emerging and Selected Topics in Power Electronics, 2023
This article presents a new modulation method based on nearest level modulation (NLM) and phase voltage level reconstruction for the four-level single flying capacitor (4L-SFC) converter.
Shima Shahnooshi   +4 more
semanticscholar   +1 more source

Deadbeat Predictive Control Algorithm for PMSM Based on Super-Twisting Sliding Mode Observer

International Conference on Electrical Machines and Systems, 2023
The deadbeat predictive control (DPC) is a widely-used technique in electric vehicle drive systems due to its ability to minimize harmonic currents and torque ripple, as well as its fast response speed. However, the DPC method is known to be sensitive to
Zongbo Hu, Jinsong Kang, Xiaodong Xue
semanticscholar   +1 more source

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