Results 51 to 60 of about 402 (282)

A Composite Model Predictive Control Method of SRMs with PWM-based Signal for Torque Ripple Suppression

, 2023
In this article, a novel composite predictive control using PWM control signals is proposed for the torque ripple suppression of the switched reluctance machine (SRM).
Dianxun Xiao, Ge, Lefei, Xiao, Dianxun, Shuai Mao, de Doncker, Rik W., Mao, Shuai, Lefei Ge, Guo, Jixuan, Song, Shoujun, Dongdong Zhao, Zhao, Dongdong, Shoujun Song, Jixuan Guo, Rik W. De Doncker   +13 more
core   +1 more source

Hybrid Control Strategy of MPC and DBC to Achieve a Fixed Frequency and Superior Robustness

Energies, 2020
In this paper, a hybrid control strategy for power converters, based on improved deadbeat control (DBC) and improved finite control set model predictive control (MPC), is proposed.
Yuhan Zhang, Guiping Du, Jiajian Li, Yanxiong Lei   +3 more
doaj   +1 more source

Performance Analysis of Current Control Strategies for Hybrid Stepper Motors

IEEE Open Journal of the Industrial Electronics Society, 2022
Hybrid stepper motors are widespread in industrial automation due to their robustness and high torque performance in low speed range, e.g. 3D printers, pick and place, and generally in many low power positioning applications.
Fabio Bernardi, Emilio Carfagna, Giovanni Migliazza, Giampaolo Buticchi, Fabio Immovilli, Emilio Lorenzani   +5 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Dynamic control strategy for bi-directional DC/DC converters to suppress the dc-link voltage fluctuation in motor driver systems

, 2023
This paper presents an improved dc-link voltage control strategy for bi-directional DC/DC converter to reduce the fluctuation of dc-link voltage. The bi-directional DC/DC converter is the top widely-adopted topology for machine drives. However, a wild dc-
Wenjuan Zhang, Haixia Zhang, Wan Feng, Mengdi Li, Shoudao Huang   +4 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Robust Predictive Control Scheme for Permanent-Magnet Synchronous Generators Based Modern Wind Turbines

, 2021
In this article, a deadbeat predictive control (DB-PC) strategy for permanent-magnet synchronous generators (PMSGs)-based modern wind turbines is proposed.
Christoph Hackl, Ralph Kennel, Mohamed Abdelrahem   +2 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source