Results 21 to 30 of about 74 (65)

Transcriptome‐Based Classification of Resected Pancreatic Ductal Adenocarcinoma Enhances Prognostic Modelling Accuracy of Overall Survival Following Adjuvant Treatment

open access: yesInternational Journal of Cancer, EarlyView.
Outcomes after resection of pancreatic ductal adenocarcinoma remain highly variable, and existing prognostic models lack sufficient accuracy. Here, the authors aimed to improve survival prediction by integrating transcriptome‐based subtyping into a validated clinical model and applying it to a multicenter real‐world cohort of fresh‐frozen resection ...
Marjolein F. Lansbergen   +20 more
wiley   +1 more source

Optimal timing to assess exercise‐induced oxidative stress: A systematic review and meta‐analysis

open access: yesExperimental Physiology, EarlyView.
Abstract There is a lack of consensus on optimal timing to assess redox biomarkers post‐exercise, limiting methodological standardisation and linking oxidative stress to physiology. We determined optimal post‐exercise oxidative stress assessment times using three redox biomarkers: glutathione, F2‐isoprostanes and protein carbonyls.
Chrysovalantis Stachteas   +12 more
wiley   +1 more source

A power quality enhanced grid voltage sensorless predictive direct power control for active front end rectifiers

open access: yes, 2017
In this research work, a power quality enhanced grid voltage sensorless deadbeat predictive direct power control (DB-DPC) approach for AC/DC power converters based on latest virtual flux (VF) estimation, DB-DPC and space vector pulse width modulation ...
Amit Kumar, Gopalakrishna Srungavarapu
core   +1 more source

Cash‐holding Benefits and Their Influence on Seasoned Equity Offering Decisions

open access: yesAbacus, Volume 62, Issue 2, Page 647-672, June 2026.
This study investigates the cash‐holding motivations of issuers with excess cash. It aims to explain why these issuers choose to accumulate even more cash through stock issuances rather than utilize their existing surplus. I assess three competing cash‐holding motivation hypotheses: whether issuers raise cash: (i) to fund the needs of future growth ...
Ebrahim Bazrafshan
wiley   +1 more source

Losartan API and Nitrosamines Impurities—Stability Profile Investigation Using HPLC, LC‐MS, and In Silico Assessment

open access: yesJournal of Separation Science, Volume 49, Issue 5, May 2026.
ABSTRACT Nitrosamines are potent genotoxic impurities with well reported mutagenic and carcinogenic effects. Their presence has been detected in several pharmaceutical products among them losartan, an angiotensin II receptor blocker. Considering the risks already reported for these impurities, the present study aimed to investigate the influence of ...
Paulo Roberto Rodrigues Martini   +6 more
wiley   +1 more source

Generation of Cloned Sheep Lacking Galactose‐α1,3‐Galactose and N‐Glycolylneuraminic Acid Antigens

open access: yesXenotransplantation, Volume 33, Issue 3, May/June 2026.
ABSTRACT Livestock have long been regarded as a potential source of donor organs to alleviate the global organ shortage for transplantation. Sheep have a similar anatomy to humans, providing the standard model for demonstrating biocompatibility and performance of biological heart valves to obtain regulatory approval for their use in transplantation ...
Sarah J. Appleby   +9 more
wiley   +1 more source

Alpha Oscillations and Conditioned Pain Modulation Is Associated With Treatment Resistance to Spinal Cord Stimulation for Neuropathic Pain

open access: yesEuropean Journal of Pain, Volume 30, Issue 4, April 2026.
ABSTRACT Background Neuropathic pain (NP) is a severe form of chronic pain associated with reduced quality of life. Spinal cord stimulation (SCS) can provide pain relief for some but not all treated, highlighting the importance of predictive markers.
Rima El‐Sayed   +8 more
wiley   +1 more source

Regional Volume of Atrial Fibrillation Catheter Ablation Is Not Associated With Increased Per Capita Medical Costs

open access: yesJournal of Arrhythmia, Volume 42, Issue 2, April 2026.
This ecological study of 47 Japanese prefectures demonstrates that regional medical costs are primarily driven by aging and chronic disease rather than atrial fibrillation catheter ablation, which was found to be a cost‐neutral intervention whose initial expenses are likely offset by the long‐term prevention of costly complications.
Takahiro Kamihara   +3 more
wiley   +1 more source

Percutaneous Versus Surgical Cannulation for Veno‐Arterial Extracorporeal Life Support: A Systematic Review and Meta‐Analysis

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Extracorporeal life support (ECLS) is a critical intervention in the management of severe cardiac and respiratory failure. Among the commonly used cannulation techniques, percutaneous cannulation (PC) and surgical cannulation (SC) are most prevalent; however, their comparative safety and effectiveness remain under debate ...
Syeda Zuha Sami   +7 more
wiley   +1 more source

Real‐Time Detection and Prevention of DoS Attack in Unmanned Marine Vehicles Using Machine Learning

open access: yesSECURITY AND PRIVACY, Volume 9, Issue 2, March/April 2026.
ABSTRACT Unmanned marine vehicles (UMVs) are one of the most crucial components of the underwater communication and surveillance system in the marine and oceanographic environment. This research introduces a novel approach to stabilize the connection in an unstable underwater environment by inheriting features of communication velocities.
Noman Ali   +8 more
wiley   +1 more source

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