Results 61 to 70 of about 141,941 (296)

Power Relations in the Preparation of the Nondiscrimination Act: The Controversial Issue of Supervising Discrimination in Working Life

open access: yesEuropean Policy Analysis, EarlyView.
ABSTRACT In the context of Europeanisation and neo‐corporatism, we examine the lengthy process of revising the Nondiscrimination Act in Finland, spanning from 2007 to 2023. The focus is on the mandate of the Nondiscrimination Ombudsman in the workplace and on explaining the sudden policy change of strengthening it after a prolonged standstill.
Laura Jauhola, Kati Rantala
wiley   +1 more source

CK2 Phosphorylates and Inhibits TAp73 Tumor Suppressor Function to Promote Expression of Cancer Stem Cell Genes and Phenotype in Head and Neck Cancer

open access: yesNeoplasia: An International Journal for Oncology Research, 2014
Cancer stem cells (CSC) and genes have been linked to cancer development and therapeutic resistance, but the signaling mechanisms regulating CSC genes and phenotype are incompletely understood. CK2 has emerged as a key signal serine/threonine kinase that
Hai Lu   +7 more
doaj   +1 more source

Genetic Hearing Loss Associated With Autoinflammation

open access: yesFrontiers in Neurology, 2020
Sensorineural hearing loss can result from dysfunction of the inner ear, auditory nerve, or auditory pathways in the central nervous system. Sensorineural hearing loss can be associated with age, exposure to ototoxic drugs or noise, or mutations in ...
Hiroshi Nakanishi   +10 more
doaj   +1 more source

New insights into applications of base editor in hereditary disorders

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai   +8 more
wiley   +1 more source

Ocular and systemic safety of a recombinant AAV8 vector for X-linked retinoschisis gene therapy: GLP studies in rabbits and Rs1-KO mice

open access: yesMolecular Therapy: Methods & Clinical Development, 2016
X-linked retinoschisis (XLRS) is a retinal disease caused by mutations in the gene encoding the protein retinoschisin (RS1) and is one of the most common causes of macular degeneration in young men.
Dario Marangoni   +12 more
doaj   +1 more source

Trends in U.S. National Institutes of Health Funding for CHARGE Syndrome Research, 2000 to 2024

open access: yes
American Journal of Medical Genetics Part A, EarlyView.
Muhammad Othman   +2 more
wiley   +1 more source

Levers of Control: Impact on Innovation

open access: yesJournal of Corporate Accounting &Finance, EarlyView.
ABSTRACT Using structural equation modeling, our study provides evidence for the effects of management control systems on innovation performance and knowledge acquisition within organizations. Our proposed model separates (1) dyadic management controls (“one‐to‐one”) from (2) polyvalent management controls (“one‐to‐team”).
Peter Letmathe, Christian Meyer
wiley   +1 more source

Bee products as alternatives in the treatment of viral infections

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba   +3 more
wiley   +1 more source

Factors Affecting Nasal Discharge in Chronic Rhinosinusitis Patients

open access: yesThe Laryngoscope, EarlyView.
This study aimed to identify patient‐specific factors influencing the severity of nasal drainage in chronic rhinosinusitis (CRS) patients. It found that postnasal discharge (PND) was the most severe symptom, with female gender, CRS without nasal polyps, prior endoscopic sinus surgery, and allergies significantly associated with severe PND.
Pranav A. Patel   +7 more
wiley   +1 more source

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