Results 71 to 80 of about 232,677 (345)

Cisplatin is retained in the cochlea indefinitely following chemotherapy

open access: yesNature Communications, 2017
Permanent hearing loss occurs in many cancer patients treated with cisplatin. In this study, the authors examine cisplatin pharmacokinetics in the cochleae of mice and humans showing that cisplatin is retained for months to years after treatment.
Andrew M. Breglio   +8 more
doaj   +1 more source

Synaptic mitochondria regulate hair-cell synapse size and function

open access: yeseLife, 2019
Sensory hair cells in the ear utilize specialized ribbon synapses. These synapses are defined by electron-dense presynaptic structures called ribbons, composed primarily of the structural protein Ribeye.
Hiu-tung C Wong   +5 more
doaj   +1 more source

Associations Between Multiple Chemosensory Dysfunction and Cognition

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
Key Points This study supports the association between chemosensory dysfunction and cognition. We introduce methods of assessing trigeminal function with the Medoc TSA‐II thermoprobe. Our results identify an association between subjective trigeminal dysfunction and cognition.
Michelle Yu   +5 more
wiley   +1 more source

GENETICS, DISABILITY, AND DEAFNESS

open access: yes, 2004
Introduction -- Pt. 1. Science, culture, and human variation - - The science of human nature and the human nature of science / Louis Menand -- The cultural context of disability / Nora Groce - - Pt. 2.
Van Cleve, John Vickrey, ed.
core  

DEAFNESS [PDF]

open access: yes, 2005
The pathology of hearing loss is a very difficult problem. The serious approach to the treatment of deafness was applied throughout centuries, especially from the fifteenth century onwards, while in Croatia from not earlier than the nineteenth century ...
Nikola Kirinčić
core   +3 more sources

Rhinology Fellowship Training in the United States: Insights From a National Survey

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The proportion of otolaryngology trainees pursuing fellowship has increased alongside rapid expansion in rhinology fellowship programs. Contemporary data evaluating trainee motivations, expectations, and outcomes remain limited. This study assesses contemporary data evaluating trainee motivations, expectations, and outcomes among US
Daniel B. Spielman   +7 more
wiley   +1 more source

Genetic etiology study of the non-syndromic deafness in Chinese Hans by targeted next-generation sequencing

open access: yesOrphanet Journal of Rare Diseases, 2013
BackgroundAlthough over 60 non-syndromic deafness genes have been identified to date, the etiologic contribution of most deafness genes remained elusive.
T. Yang   +4 more
semanticscholar   +1 more source

Post-Irradiation Sudden Deafness

open access: yes, 2009
As in radiation-induced cancer, post-irradiation sudden deafness (PISD) is defined as sudden onset deafness in patients post-irradiation. Fifteen nasopharyngeal carcinoma (NPC) patients with PISD were enrolled in this study.
楊怡和;婁培人   +1 more
core  

Understanding Sustainable Business Model Barriers: The Interplay of Sustainable Value Dynamics and Organizational Tensions

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Sustainability‐oriented startups face challenges in implementing sustainable business models due to resource constraints, technological uncertainty and competing economic, social and environmental objectives. Although prior studies have identified numerous sustainable business model barriers, limited attention has been given to the ...
Sandra Naomi Morioka   +2 more
wiley   +1 more source

A novel G21R mutation of the GJB2 gene causes autosomal dominant non-syndromic congenital deafness in a Cuban family

open access: yesGenetics and Molecular Biology, 2006
Deafness is a complex disorder affecting 1/1000 infants. In developed countries, more than 50% of deafness cases are thought to have a genetic cause. At least 40 loci for dominant non-syndromic deafness and another 30 for recessive non-syndromic deafness
Raquel Rabionet   +4 more
doaj   +1 more source

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