Results 161 to 170 of about 550,989 (293)

Proximal anatomical axes show bidirectional variability: Accurate tibial slope requires mechanical axis measurement

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To determine whether posterior tibial slope (PTS) measured to proximal anatomical axes can serve as a reliable proxy for PTS measured to the mechanical tibial axis (mTA). Methods In patients ≥18 years with failed anterior cruciate ligament reconstruction, medial and lateral PTS were measured relative to the mTA on a lateral lower‐leg ...
Barbara C. Boer   +6 more
wiley   +1 more source

Longitudinal Analysis of Oral Potentially Malignant Disorder Conversion to Malignancy

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objectives Oral potentially malignant disorders (OPMDs) are local and systemic conditions that can result in oral malignancies. We have had an OPMD surveillance program for 25 years covering over 30% of our state's population. More recent electronic health record search techniques have allowed us to analyze over 1500 patients in over a 10‐year
Benjamin Palatnik   +4 more
wiley   +1 more source

Investigating Tuberculosis Dynamics Under Various Control Strategies: A Comprehensive Analysis Using Real Statistical Data

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In the present investigation, a mathematical model with vaccination, treatment, and environmental impact under real data is presented. Initially, we present the model without any interventions, followed by an examination of its equilibrium points.
Bashir Al‐Hdaibat   +4 more
wiley   +1 more source

Energetic efficiency of mixing in a periodically reoriented Dean flow

open access: yesChemical and Process Engineering, 2023
Rożeń, Antoni, Kopytowski, Janusz
openaire   +1 more source

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System

open access: yesChemistryOpen, EarlyView.
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz   +10 more
wiley   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

open access: yesChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel   +5 more
wiley   +1 more source

Policy Capacity Matters Differently Over Time: The Emergence and Persistence of Participatory Budgeting in China

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT The persistence of participatory budgeting (PB) in selected Chinese localities challenges the conventional wisdom that deliberative democratic practices can only take root in liberal political environments. Yet, existing literature has not sufficiently elucidated the factors underpinning the rise and sustained operation of PB in this seemingly
Yifei Yan   +3 more
wiley   +1 more source

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