Results 31 to 40 of about 8,927 (215)

Impact of Dean Vortices on the Integrity Testing of a Continuous Viral Inactivation Reactor [PDF]

open access: yesBiotechnology Journal, 2018
We propose a standard protocol for integrity testing the residence‐time distribution (RTD) in a “Jig in a Box” design (JIB)—a previously described tortuous‐path, tubular, low‐pH, continuous viral inactivation reactor, ensuring that biopharmaceutical products will be incubated for the required minimum residence time, tmin .
Linus, Amarikwa   +3 more
openaire   +2 more sources

Effect of Dean Vortices on Heat Transfer Characteristics of Square Channel Spiral Coil Sub-cooled Condenser

open access: yesInternational Journal of Automotive Engineering, 2019
Due to the excellent heat transfer characteristics, the spiral coil sub-cooled condenser(SCSCC) has a bright application for the prospective automotive air-conditioning system. The engine load and emissions can be diminished by increasing the coefficient
Hardeep Singh   +4 more
doaj   +1 more source

Numerical investigation of Dean vortex evolution in turbulent flow through 90° pipe bends

open access: yesFrontiers in Mechanical Engineering
The current study focuses on numerically simulating turbulent flow in a 90° pipe bend using the k-ε turbulence model. Following validation of present numerical approach against prior experimental findings, extensive research was conducted to elucidate ...
Prasun Dutta   +5 more
doaj   +1 more source

Evaluation of shaft forces in a vertical canned motor through local hydraulic loss analysis

open access: yesAdvances in Mechanical Engineering, 2018
In order to improve the stability and the lifespan of rotating components in a canned motor of a centrifugal pump, a local hydraulic loss analysis has been performed based on detailed flow field analysis by Reynolds-averaged Navier–Stokes–based re ...
Miao Guo   +4 more
doaj   +1 more source

The Impact of Volute Aspect Ratio on the Performance of a Mixed Flow Turbine

open access: yesAerospace, 2017
Current trends in the automotive industry towards engine downsizing mean turbocharging now plays a vital role in engine performance. A turbocharger increases charge air density using a turbine to extract waste energy from the exhaust gas to drive a ...
Samuel P. Lee   +3 more
doaj   +1 more source

A numerical study of flow characteristics in a helical pipe

open access: yesAdvances in Mechanical Engineering, 2016
Flow characteristics and loss mechanism inside the helical pipe with large-caliber and large-scale Dean number were analyzed in this study. Numerical simulation was carried out for exploring velocity distribution, pressure field, and secondary flow by ...
Lingdi Tang, Yue Tang, Siva Parameswaran
doaj   +1 more source

Optofluidic fabrication for 3D-shaped particles. [PDF]

open access: yes, 2015
Complex three-dimensional (3D)-shaped particles could play unique roles in biotechnology, structural mechanics and self-assembly. Current methods of fabricating 3D-shaped particles such as 3D printing, injection moulding or photolithography are limited ...
Chung, Aram J   +2 more
core   +1 more source

Preservation of Extracellular Vesicle Integrity and Cargo Using Spiral Microfluidic Chip‐Based Separation

open access: yesAdvanced Materials Technologies, EarlyView.
A spiral microfluidic chip is compared with ultrafiltration for the separation of extracellular vesicles (EVs). The method preserves miRNA cargo and membrane integrity more effectively, resulting in intact vesicle morphology and consistent surface biomarker expression.
Huiseop Lee   +5 more
wiley   +1 more source

Particle transport in turbulent curved pipe flow

open access: yes, 2016
Direct numerical simulations (DNS) of particle-laden turbulent flow in straight, mildly curved and strongly bent pipes are performed in which the solid phase is modelled as small heavy spherical particles. A total of seven populations of dilute particles
Brandt, Luca   +3 more
core   +1 more source

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

open access: yesAdvanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie   +7 more
wiley   +1 more source

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