Results 251 to 260 of about 462,679 (319)

Suspected marsh mallow (Malva parviflora) toxicosis in ponies—Case cluster including an asymptomatic survivor

open access: yesAustralian Veterinary Journal, EarlyView.
There is limited published information on Malva parviflora toxicosis in horses. Four previously reported cases all resulted in death or euthanasia. The aim of this cluster investigation was to describe historical, clinical and clinicopathological findings of four ponies with suspected M.
J Bauquier   +3 more
wiley   +1 more source

Late‐onset multiple system atrophy: Neuropathological features associated with slow disease progression

open access: yesBrain Pathology, EarlyView.
Late‐onset multiple system atrophy (LO‐MSA; onset ≥75 years) shows milder degeneration of the striatonigral and olivopontocerebellar systems and serotonergic neurons in the ventrolateral medulla than usual‐age‐onset MSA with a similar disease duration. LO‐MSA may therefore exhibit slower pathological progression.
Misato Ozawa   +13 more
wiley   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

Cardiogenetics: Closing the knowledge gap in India. [PDF]

open access: yesIndian Pacing Electrophysiol J
Chockalingam P, Wilde AAM.
europepmc   +1 more source

Matrix metalloproteinase inhibition protects against junctophilin‐2 proteolysis during doxorubicin‐induced cardiotoxicity

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Treatment of cancer patients with anthracyclines is known to cause dose‐dependent cardiotoxicity through several mechanisms including enhanced oxidative stress, ultimately resulting in defective excitation–contraction coupling.
Wesam Bassiouni   +9 more
wiley   +1 more source

Organoid Models to Study Human Infectious Diseases

open access: yesCell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu   +4 more
wiley   +1 more source

Drugs and Drowning: The Toxicology of Adult Drownings in Baths and Hot Tubs in Australia, 2015–2024

open access: yesDrug and Alcohol Review, EarlyView.
ABSTRACT Introduction Drowning is the third leading cause of unintentional injury death. We aimed to determine the toxicology and circumstances of all adult drowning deaths that occurred in bath/hot tubs in Australia over the period 2015–2024. Methods Retrospective study of all adult (≥ 15 years) drowning deaths in baths or hot tubs in Australia (1 ...
Shane Darke   +4 more
wiley   +1 more source

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