Results 91 to 100 of about 872,057 (294)

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

Advanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan, Peng Li, Yue Wang, Xin Qi, Wanyu Wang, Yongzhong Cheng, Huabin Zhang, Xin Hu, Xiang Gao   +8 more
wiley   +1 more source

All Solid Lithium Metal‐Polymer Battery End‐of‐Life: an Investigation of Symmetric, Battery, and Bilayer Cells

Advanced Science, EarlyView.
In this study, the evolution of the lithium (Li)/polymer interface is compared in a realistic pouch cell configuration, either in Li/Li symmetric cell or in full Li/LiFePO4${\rm LiFePO}_4$ batteries thanks to X‐ray micro‐tomography. While Li/Li symmetric cells are the reference cell for probing the interface stability, results demonstrated that the end‐
Lucile Magnier, Didier Devaux, Jérôme Adrien, Ce Xiao, Philippe Dumaz, Margaud Lécuyer, Marc Deschamps, Eric Maire, Renaud Bouchet   +8 more
wiley   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Maturation of human induced pluripotent stem cell-derived cardiomyocytes promoted by Brachyury priming

Scientific Reports
Cardiac differentiation of human induced pluripotent stem cells is readily achievable, yet derivation of mature cardiomyocytes has been a recognized limitation.
Parisa K. Kargaran, Armin Garmany, Ramin Garmany, Marissa J. Stutzman, Maryam Sadeghian, Michael J. Ackerman, Carmen M. Perez-Terzic, Andre Terzic, Atta Behfar   +8 more
doaj   +1 more source

Entanglement Sudden Death in Band Gaps

, 2009
Using the pseudomode method, we evaluate exactly time-dependent entanglement for two independent qubits, each coupled to a non-Markovian structured environment.
A. Wallraff, B. Bellomo, B. Bellomo, B.M. Garraway, B.M. Garraway, C.E. López, D.L. Moehring, E. Hagley, G. C. Guo, G. Gordon, H. Häffner, H.-P. Breuer, J. Laurat, J. Majer, J.H. Eberly, L. Diósi, L. Viola, M. Konópka, M. Lewenstein, M.P. Almeida, R.F. Nabiev, S. Maniscalco, S. Osnaghi, T. Yu, T. Yu, W.K. Wootters, Y. J. Xia, Y. J. Zhang, Y.J. Zhang, Z. X. Man   +29 more
core   +1 more source

The Faraday Scalpel: Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models

Advanced Science, EarlyView.
Direct‐current produces nerve lesioning through discrete electrochemical reactions. Using hypoxia‐sensitive locust nerves and hypoxia‐tolerant leech nerves, we map three injury pathways: cathodic oxygen reduction, cathodic alkalization, and anodic chloride oxidation. These findings establish electrochemical lesioning—the “Faraday Scalpel”—as a precise,
Petra Ondráčková, Jan Švec, Marie Jakešová, Jiří Ehlich, Imrich Gablech, Eric Daniel Głowacki   +5 more
wiley   +1 more source

A smart headband for multimodal physiological monitoring in human exercises

Advanced Science, EarlyView.
A novel smart headband incorporating a thermal‐sensation‐based electronic skin is presented for continuous and accurate multimodal physiological monitoring, including pulse waveforms, total metabolic energy expenditure, heart rate, and forehead temperature, across both static and dynamic daily activities.
Shiqiang Liu, Guanxing Chen, Jingyi Peng, Shuo Tian, Qian Mao, Caise Wei, Jinfeng Yuan, Rong Zhu   +7 more
wiley   +1 more source

Neurochemical Alterations in Sudden Unexplained Perinatal Deaths—A Review

Frontiers in Pediatrics, 2018
Sudden unexpected perinatal collapse is a major trauma for the parents of victims. Sudden infant death syndrome (SIDS) is unexpected and mysterious death of an apparently healthy neonate from birth till 1 year of age without any known causes, even after ...
Nazeer Muhammad, Muhammad Sharif, Javeria Amin, Riffat Mehboob, Riffat Mehboob, Syed Amir Gilani, Nargis Bibi, Nargis Bibi, Hasnain Javed, Naseer Ahmed, Naseer Ahmed, Naseer Ahmed   +11 more
doaj   +1 more source

Entanglement dynamics of bipartite system in squeezed vacuum reservoirs

, 2010
Entanglement plays a crucial role in quantum information protocols, thus the dynamical behavior of entangled states is of a great importance. In this paper we suggest a useful scheme that permits a direct measure of entanglement in a two-qubit cavity ...
Aurelian Isar, Ban M, Benatti F, Dodonov A V, Duan L M, Isar A, Prauzner-Bechcicki J S, Sandulescu A, Serafini A   +8 more
core   +2 more sources