Results 91 to 100 of about 605,432 (227)

Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction

open access: yesAdvanced Science, EarlyView.
Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu   +14 more
wiley   +1 more source

Genetic testing and evidence of a founder mutation in a hotspot for hereditary transthyretin amyloidosis

open access: yesScientific Reports
Variant transthyretin (ATTRv) amyloidosis is a rare, inherited disorder caused by mutations in the TTR gene, leading to amyloid fibril deposition. The Balearic Islands are a known endemic focus for the NP_000362.1:p.Val50Met (V30M) variant, one of the ...
Marc Ventayol-Guirado   +21 more
doaj   +1 more source

A Novel Cranial Bone Transport Technique Repairs Skull Defect and Minimizes Brain Injury Outcome in Traumatic Brain Injury Rats

open access: yesAdvanced Science, EarlyView.
This study introduces a novel, safe, and effective surgical technique: Cranial bone transport (CBT) to improve traumatic brain injury (TBI) outcomes in rats. CBT significantly accelerated skull defect bone repair in addition to its promoting effects on neurological function recovery. This work provides an alternative therapy for patients suffering from
Shanshan Bai   +20 more
wiley   +1 more source

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

open access: yesAdvanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez   +20 more
wiley   +1 more source

Biomarkers of axonal damage to favor early diagnosis in variant transthyretin amyloidosis (A-ATTRv)

open access: yesScientific Reports
Early identification of ATTRv amyloidosis disease onset is still often delayed due to the lack of validated biomarkers of this disease. Light chain neurofilament (NfL) have shown promising results in early diagnosis in this disease, but data is still ...
Juan González-Moreno   +12 more
doaj   +1 more source

Entanglement dynamics of bipartite system in squeezed vacuum reservoirs

open access: yes, 2010
Entanglement plays a crucial role in quantum information protocols, thus the dynamical behavior of entangled states is of a great importance. In this paper we suggest a useful scheme that permits a direct measure of entanglement in a two-qubit cavity ...
Aurelian Isar   +8 more
core   +2 more sources

Bi‐Functional Diaminopropane Additive Enables Stable Li Anodes and Highly Efficient Cathodes for High‐Performance Li‐Air Batteries

open access: yesAdvanced Science, EarlyView.
Diaminopropane (DAP) solvent is employed as a bi‐functional additive for Li‐air batteries. It spontaneously reacts to form a gel layer to prevent corrosion on the Li anode and maintain a liquid state at the cathode to improve the decomposition of Li2O2.
Honghao Hu   +8 more
wiley   +1 more source

Sudden death of effective entanglement

open access: yes, 2010
Sudden death of entanglement is a well-known effect resulting from the finite volume of separable states. We study the case when the observer has a limited measurement capability and analyse the effective entanglement, i.e.
I. L. Chuang   +4 more
core   +1 more source

In Vitro Monitoring of Babesia microti Infection Dynamics in Whole Blood Microenvironments

open access: yesAdvanced Science, EarlyView.
Here, an open microfluidic platform termed “µ‐Blood” is reported for real‐time, continuous monitoring of Babesia microti infection dynamics in vitro. µ‐Blood allows direct interrogation of whole blood with preserved integrity of the original whole blood microenvironment through an extended period (e.g., 72 h with mouse red blood cells) ex vivo. µ‐Blood
Chao Li   +4 more
wiley   +1 more source

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