Results 131 to 140 of about 10,817,722 (406)

Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy [PDF]

open access: gold, 2020
Christine Fung   +5 more
openalex   +1 more source

From the Dissolution of the Anima to the End of All Things [PDF]

open access: yes, 2018
In the present paper I analyze the theme of death in Gothic Metal songs such as Forever Failure by Paradise Lost, Everything Dies by Type O Negative, The Hanged Man by Moonspell or Gone with The Sin by HIM. The subthemes I am mostly interested in are the
Bolea, Ștefan
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

PTEN modulates EGFR late endocytic trafficking and degradation by dephosphorylating Rab7

open access: yesNature Communications, 2016
Rab7 is a critical GTPase for endosome maturation and it is implicated in the endocytic traffic of several receptors, including EGFR. In this study, the authors reveal the potential role of PTEN in the endocytic trafficking pathway of EGFR, which is ...
Swapnil Rohidas Shinde   +1 more
doaj   +1 more source

Magneto mitochondrial dysfunction mediated cancer cell death using intracellular magnetic nano-transducers

open access: green, 2021
Wooram Park   +6 more
openalex   +2 more sources

Death [PDF]

open access: yesAcademic Emergency Medicine, 2020
openaire   +2 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Epigenetic Rewiring of Protein Kinase Signalling in T-Cell Acute Lymphoblastic Leukaemia

open access: yesKinases and Phosphatases
T-cell acute lymphoblastic leukaemia (T-ALL) is an aggressive neoplastic malignancy characterised by the accumulation of multiple oncogenic and epigenetic alterations in haematopoietic T-cell precursors leading to their uncontrolled proliferation and ...
Claudina A. Pérez-Novo   +6 more
doaj   +1 more source

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