Results 111 to 120 of about 8,324,430 (306)
Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair
Nature Communications, 2017 The role of annexins in cell membrane repair is largely undefined. Here the authors use a model lipid bilayer to show that annexin A4 induces curvature at the membrane free edge and annexin A6 induces constriction force, and find that both annexins are ...
Theresa Louise Boye +7 more
doaj +1 more source
Rare as Hens\u27 Teeth: The New Geography of the American Death Penalty [PDF]
, 2016 Today, only a few dozen scattered counties actually impose death sentences, supporting the death penalty’s ...
Garrett, Brandon L.
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, Volume 20, Issue 6, Page 1612-1625, June 2026.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Identifying Catholic School Teachers Attitudes and Perceptions about Death and Grief [PDF]
, 2006 Death and grief are not frequently discussed with children as a normal part of life. Previous studies show that teachers are not comfortable discussing the subject in the classrooms.
Higdon, Stephania Ann
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 2017 On Pain of Death is a fictional retelling of the story of Sir Pelleas, who, in Thomas Malory’s Le Morte D’Arthur, is depicted as a noble knight with unrequited love for Lady Ettarde.
Cummings, Declan
core +1 more source
High Death Rates: More Deaths or Earlier Deaths?
Journal of the Royal College of Physicians of London, 1987 In the analysis of mortality statistics high age-specific death rates could be interpreted as meaning more deaths (more disease), but they could equally well be interpreted as meaning earlier deaths (death at younger age). The distinction markedly affects the choice of hypotheses that may be advanced to explain variations in person, time and place and ...
openaire +2 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Autophagy ReportsDisrupted intestinal homeostasis and barrier function contribute to the development of diseases such as inflammatory bowel disease. BECLIN-1, a core component of two class III phosphatidylinositol 3 kinase complexes, has a dual role in autophagy and ...
Juliani Juliani +10 more
doaj +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source