Results 171 to 180 of about 10,817,722 (406)

Regulation of Ferroptotic Cancer Cell Death by GPX4

Cell, 2014
W. Yang, Rohitha Sriramaratnam, Matthew E. Welsch, K. Shimada, R. Skouta, V. Viswanathan, J. Cheah, P. Clemons, Alykhan F. Shamji, C. Clish, L. Brown, A. Girotti, V. Cornish, S. Schreiber, B. Stockwell   +14 more
semanticscholar   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

TMBIM6 INHIBITS APOPTOSIS OF VULNERABLE NEURONS IN PARKINSON´S DISEASE

IBRO Neuroscience Reports, 2023
Pablo Ahumada Montalva, Carolina Jerez, Sara Borquez, Francisco Muñoz, Melissa Nassif, Mario Sanhueza, Rene Vidal, Diego Rojas Rivera   +7 more
doaj   +1 more source

Age at onset and clinical course of RBM20-mediated cardiomyopathy

Scientific Reports
Disease-causative variants in RBM20-encoded RNA-binding motif protein 20 cause a severe arrhythmogenic dilated cardiomyopathy (DCM). We aimed to characterize the clinical course of RBM20-mediated DCM in comparison to other familial and non-familial forms
Ramin Garmany, Matteo Castrichini, Raquel Neves, Naveen L. Pereira, Ciorsti MacIntyre, Jay W. Schneider, Michael J. Ackerman, John R. Giudicessi   +7 more
doaj   +1 more source

Global causes of maternal death: a WHO systematic analysis.

Lancet Global Health, 2014
L. Say, D. Chou, Alison Gemmill, Alison Gemmill, Ö. Tunçalp, Ann-Beth Moller, J. Daniels, A. M. Gülmezoglu, M. Temmerman, L. Alkema   +9 more
semanticscholar   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

p53-Dependent and -Independent Pathways of Apoptotic Cell Death in Sepsis [PDF]

, 2000
Richard S. Hotchkiss, Kevin W. Tinsley, Jia–Ji Hui, Katherine Chang, Paul E. Swanson, Anne M. Drewry, Timothy G. Buchman, Irene E. Karl   +7 more
openalex   +1 more source

Perch essence prevents cell death to improve skeletal muscle mass and strength: Evidence from in vitro and human model

, 2023
Chih‐Cheng Lin, Chih‐Yu Hsieh, Ling-Ni Chen, Mao‐Hsiang Lee, Yi-Han Ting, Ting‐Ming Wang, Jia‐Feng Chang   +6 more
openalex   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

The Death and Life of Great American Cities

, 1962
J. Jacobs
semanticscholar   +1 more source