Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Exploring perspectives regarding death cafés for people experiencing homelessness: a qualitative study. [PDF]
Crooks J+6 more
europepmc +1 more source
Death, near death, and an antibiotic [PDF]
openaire +3 more sources
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
A Narrative Overview of Fatal Myocarditis in Infant with Focus on Sudden Unexpected Death and Forensic Implications. [PDF]
Sacco MA+6 more
europepmc +1 more source
A Case in Which Acute Spasmodic Pain in the Left Lower Extremity Was Completely Relieved by Sub-Dural Division of the Posterior Roots of Certain Spinal Nerves, All other Treatment Having Proved Useless. Death from Sudden Collapse and Cerebral Hæmorrhage on the Twelfth Dat after the Operation, at the Commencement of Apparent Convalescence [PDF]
William H. Bennett
openalex +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
Foetal Deaths from Antenatal Anticoagulant Therapy [PDF]
R.R. Gordon, Taraneh Dean
openalex +1 more source
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner+6 more
wiley +1 more source
Community nurses' willingness to implement Advance Care Planning (ACP) and their attitudes toward death: current status and correlation analysis. [PDF]
Peng Q, Dong Y, Dai Q, Zhang C, Li X.
europepmc +1 more source