Results 181 to 190 of about 5,450,952 (343)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Exploring perspectives regarding death cafés for people experiencing homelessness: a qualitative study. [PDF]

BMJ Open
Crooks J, Davis G, Pattinson M, Casey E, Shulman C, Flemming K, Hudson B.   +6 more
europepmc   +1 more source

Death, near death, and an antibiotic [PDF]

Journal of Nuclear Cardiology, 2018
openaire   +3 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

A Narrative Overview of Fatal Myocarditis in Infant with Focus on Sudden Unexpected Death and Forensic Implications. [PDF]

J Clin Med
Sacco MA, Gualtieri S, Verrina MC, Aquila VR, Tarda L, Tarallo AP, Aquila I.   +6 more
europepmc   +1 more source

A Case in Which Acute Spasmodic Pain in the Left Lower Extremity Was Completely Relieved by Sub-Dural Division of the Posterior Roots of Certain Spinal Nerves, All other Treatment Having Proved Useless. Death from Sudden Collapse and Cerebral Hæmorrhage on the Twelfth Dat after the Operation, at the Commencement of Apparent Convalescence [PDF]

, 1889
William H. Bennett
openalex   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Foetal Deaths from Antenatal Anticoagulant Therapy [PDF]

, 1955
R.R. Gordon, Taraneh Dean
openalex   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Community nurses' willingness to implement Advance Care Planning (ACP) and their attitudes toward death: current status and correlation analysis. [PDF]

Front Med (Lausanne)
Peng Q, Dong Y, Dai Q, Zhang C, Li X.
europepmc   +1 more source