Results 181 to 190 of about 10,817,722 (406)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Recognizing animal suffering and death in medicine [PDF]

, 2001
John B. Lynch
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Improvement of liver injury and survival by JNK2 and iNOS deficiency in liver transplants from cardiac death mice

, 2015
Qinlong Liu, Hasibur Rehman, Yasodha Krishnasamy, Rick G. Schnellmann, John J. Lemasters, Zhi Zhong   +5 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Gender differences in the effect of occupational endotoxin exposure on impaired lung function and death: the Shanghai Textile Worker Study

, 2013
Peggy S. Lai, Jing Hang, Feng Ying Zhang, Xinyi Lin, Bu Yong Zheng, Hei Lian Dai, Li Su, Tianxi Cai, David C. Christiani   +8 more
openalex   +2 more sources

EFFECTS OF ESSENTIAL CAREGIVER POLICIES ON COVID-19 AND NON-COVID-19 DEATHS IN NURSING HOMES [PDF]

, 2023
R. Tamara Konetzka, Nadia Ghazali, Mingyu Qi   +2 more
openalex   +1 more source

Serious Illness and Death [PDF]

, 2000
Riga, Peter J.
core   +2 more sources

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Science, 2001
M. Wei, W. Zong, E. Cheng, T. Lindsten, V. Panoutsakopoulou, Andrea J. Ross, K. Roth, G. MacGregor, C. Thompson, S. Korsmeyer   +9 more
semanticscholar   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source