Results 231 to 240 of about 10,817,722 (406)

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Exploring cell death mechanisms in liver transplantation: implications for graft survival. [PDF]

Front Immunol
Hirao H, Watanabe T, Uchida Y, Hatano E.
europepmc   +1 more source

The coronial reporting of medical-setting deaths: A legal analysis of the variation in Australian jurisdictions

, 2014
Sarah Middleton, Michael Buist
openalex   +2 more sources

The relationship of breast cancer deaths with age groups and urbanization of the population: a multi-country analysis

, 2022
Çetin Altunal, İbrahim Tayfun Şahiner
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Correction: Tumor-derived exosomal tsRNA 3'tiRNA-AlaCGC in promoting fibroblast senescence and Galectin-9 secretion to induce immune tolerance in lung adenocarcinoma. [PDF]

Cell Death Discov
Zhao G, Zhang Y, Zhang H, Guo Y, Xu C, Ge D, Gu J.   +6 more
europepmc   +1 more source

Human Death as Neocortical Death: The Ethical Context [PDF]

, 1974
Weber, Leonard J.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Trends and risk factors for suicide mortality in India from 2001-2019: National mortality study. [PDF]

PLOS Glob Public Health
Suraweera W, Amarasekera S, Vijayakumar L, Seshadri SR, Brown P, Karunarathne A, Eddleston M, Jha P.   +7 more
europepmc   +1 more source

Spontaneous liver haematoma rupture associated with pre-eclampsia in a low- to middle-income country: Lessons to be learnt from maternal death assessments

, 2018
Jagidesa Moodley, Nnabuike Chibuoke Ngene   +1 more
openalex   +2 more sources