Results 251 to 260 of about 10,817,722 (406)

ARTICLE: A Statistical Analysis of Predictors Associated with the Dramatic Decline in Death Sentences in the United States in the Last Two Decades [PDF]

, 2019
Talia Roitberg Harmon, David McCord
openalex   +1 more source

Mortality in sickle cell disease. Life expectancy and risk factors for early death.

New England Journal of Medicine, 1994
O. Platt, D. Brambilla, W. Rosse, P. Milner, O. Castro, M. Steinberg, P. Klug   +6 more
semanticscholar   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Editorial Expression of Concern: USP2a alters chemotherapeutic response by modulating redox. [PDF]

Cell Death Dis
Benassi B, Marani M, Loda M, Blandino G.
europepmc   +1 more source

The Outcome of Death or Moderate-to-Severe Bronchopulmonary Dysplasia in Extremely Low Birth Weight Infants is Equivalent with Bilevel- or Ventilator-Delivered Nasal Intermittent Positive Pressure Ventilation [PDF]

, 2013
B Lemyre, D Millar, B Yoder, A Chiu, R Roberts, H Kirpalani   +5 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Cell death: critical control points.

Cell, 2004
N. Danial, S. Korsmeyer
semanticscholar   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

State-Level Implementation of Health and Safety Policies to Prevent Sudden Death and Catastrophic Injuries Within Secondary School Athletics: Letter to the Editor [PDF]

, 2018
Michael C. Koester, Samuel T. Johnson, Marc F. Norcross   +2 more
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source