Results 51 to 60 of about 10,817,722 (406)
Copper metabolism in cell death and autophagy
Autophagy, 2023 Copper is an essential trace element in biological systems, maintaining the activity of enzymes and the function of transcription factors. However, at high concentrations, copper ions show increased toxicity by inducing regulated cell death, such as ...Qian Xue, Rui Kang, D. Klionsky, D. Tang, Jinbao Liu, Xin Chen +5 moresemanticscholar +1 more sourceThe MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction
We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly +8 morewiley +1 more sourceStereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives
Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy +13 morewiley +1 more sourceUrsolic Acid Impairs Cellular Lipid Homeostasis and Lysosomal Membrane Integrity in Breast Carcinoma Cells
Cells, 2022 Cancer is one of the leading causes of death worldwide, thus the search for new cancer therapies is of utmost importance. Ursolic acid is a naturally occurring pentacyclic triterpene with a wide range of pharmacological activities including anti ...Ditte L. Fogde, Cristina P. R. Xavier, Kristina Balnytė, Lya K. K. Holland, Kamilla Stahl-Meyer, Christoffel Dinant, Elisabeth Corcelle-Termeau, Cristina Pereira-Wilson, Kenji Maeda, Marja Jäättelä +9 moredoaj +1 more sourceDeath Bed [PDF]
, 2006 Lethal injection is this country\u27s primary method of execution, adopted for use by all but one of the thirty-seven death penalty states, as well as the federal government.Denno, Deborah W.core +1 more sourceApoptotic cell death in disease—Current understanding of the NCCD 2023
Cell Death and Differentiation, 2023 Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have elucidated the key contribution of this ...I. Vitale, F. Pietrocola, Emma Guilbaud, Stuart A. Aaronson, J. Abrams, D. Adam, M. Agostini, P. Agostinis, E. Alnemri, L. Altucci, I. Amelio, D. Andrews, R. Aqeilan, E. Arama, E. Baehrecke, Siddharth Balachandran, D. Bano, N. Barlev, J. Bartek, N. Bazan, C. Becker, F. Bernassola, M. Bertrand, M. Bianchi, M. Blagosklonny, J. Blander, G. Blandino, K. Blomgren, C. Borner, C. Bortner, P. Bove, P. Boya, C. Brenner, P. Brož, T. Brunner, R. Damgaard, G. Calin, M. Campanella, E. Candi, M. Carbone, D. Carmona‐Gutierrez, F. Cecconi, F. K. Chan, Guoqiang Chen, Quan Chen, Youhai H. Chen, E. Cheng, J. Chipuk, J. Cidlowski, A. Ciechanover, G. Ciliberto, M. Conrad, J. Cubillos-Ruiz, P. Czabotar, V. D’Angiolella, M. Daugaard, T. Dawson, V. Dawson, R. De Maria, B. de Strooper, K. Debatin, R. Deberardinis, A. Degterev, G. Del Sal, M. Deshmukh, F. Di Virgilio, M. Diederich, Scott J. Dixon, B. Dynlacht, W. El-Deiry, J. Elrod, K. Engeland, G. Fimia, C. Galassi, C. Ganini, A. García-Sáez, Abhishek D Garg, C. Garrido, E. Gavathiotis, M. Gerlic, Sourav Ghosh, D. Green, L. Greene, H. Gronemeyer, G. Häcker, G. Hajnóczky, J. Hardwick, Y. Haupt, Sudan He, D. Heery, M. Hengartner, C. Hetz, David A Hildeman, H. Ichijo, Satoshi Inoue, M. Jäättelä, Ana Janic, B. Joseph, Philipp J Jost, T. Kanneganti, M. Karin, H. Kashkar, T. Kaufmann, G. Kelly, O. Kepp, A. Kimchi, R. Kitsis, D. Klionsky, R. Kluck, D. Krysko, D. Kulms, Sharad Kumar, S. Lavandero, I. Lavrik, J. Lemasters, Gianmaria Liccardi, A. Linkermann, S. Lipton, R. Lockshin, C. López-Otín, T. Luedde, M. MacFarlane, F. Madeo, W. Malorni, G. Manic, R. Mantovani, S. Marchi, J. Marine, S. Martin, J. Martinou, P. Mastroberardino, J. Medema, P. Mehlen, P. Meier, G. Melino, S. Melino, Edward A. Miao, U. Moll, C. Muñoz-Pinedo, D. Murphy, M. Niklison-Chirou, F. Novelli, G. Núñez, A. Oberst, D. Ofengeim, J. Opferman, M. Oren, M. Pagano, T. Panaretakis, M. Pasparakis, J. Penninger, F. Pentimalli, David M. Pereira, S. Pervaiz, M. Peter, P. Pinton, Giovanni Porta, J. Prehn, H. Puthalakath, G. Rabinovich, K. Rajalingam, K. Ravichandran, M. Rehm, J. Ricci, R. Rizzuto, N. Robinson, C. Rodrigues, B. Rotblat, C. Rothlin, D. Rubinsztein, T. Rudel, A. Rufini, K. Ryan, K. Sarosiek, A. Sawa, E. Sayan, K. Schroder, L. Scorrano, F. Sesti, F. Shao, Yufang Shi, G. Sica, J. Silke, H. Simon, A. Sistigu, A. Stephanou, B. Stockwell, Flavie Strapazzon, A. Strasser, Liming Sun, E. Sun, Qiang Sun, G. Szabadkai, S. Tait, D. Tang, Nektarios Tavernarakis, C. Troy, B. Turk, N. Urbano, P. Vandenabeele, T. Vanden Berghe, M. V. Vander Heiden, J. Vanderluit, A. Verkhratsky, A. Villunger, S. von Karstedt, A. Voss, K. Vousden, D. Vučić, Daniela Vuri, E. Wagner, H. Walczak, D. Wallach, Ruoning Wang, Ying Wang, Achim Weber, Will Wood, T. Yamazaki, Huang-Tian Yang, Z. Zakeri, J. Zawacka-Pankau, Lin Zhang, Haibing Zhang, B. Zhivotovsky, Wenzhao Zhou, M. Piacentini, G. Kroemer, L. Galluzzi +227 moresemanticscholar +1 more sourceParent‐to‐Child Information Disclosure in Pediatric Oncology
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik +12 morewiley +1 more sourceThe convergence of radiation and immunogenic cell death signaling pathways. [PDF]
, 2012 Ionizing radiation (IR) triggers programmed cell death in tumor cells through a variety of highly regulated processes. Radiation-induced tumor cell death has been studied extensively in vitro and is widely attributed to multiple distinct mechanisms ...Barcellos-Hoff, Mary H, Demaria, Sandra, Formenti, Silvia C, Golden, Encouse B, Pellicciotta, Ilenia +4 morecore +2 more sources