Results 31 to 40 of about 8,324,430 (306)

“They want you to know who they really are inside of the old visage”—biographical storytelling as a methodological tool to explore emotional challenges in old age

BMC Geriatrics, 2023
Background Growing older is often associated with resilience, contentedness and inner growth. Older people however are also at risk of confronting unique emotional challenges as a result of varied ageing-related experiences.
Chao Fang, Alastair Comery, Sam Carr
doaj   +1 more source

Adverse effects of prenatal tobacco smoke exposure on biological parameters of the developing brainstem

Neurobiology of Disease, 2005
We aimed to study the consequences of chronic exposure to tobacco smoke in utero on the morphological and functional maturation of the brainstem by comparing stillbirths of smoker mothers versus nonsmoker mothers.
Anna Maria Lavezzi, Giulia Ottaviani, Luigi Matturri   +2 more
doaj   +1 more source

Lysosomal Changes in Mitosis

Cells, 2022
The recent discovery demonstrating that the leakage of cathepsin B from mitotic lysosomes assists mitotic chromosome segregation indicates that lysosomal membrane integrity can be spatiotemporally regulated.
Jonathan Stahl-Meyer, Lya Katrine Kauffeldt Holland, Bin Liu, Kenji Maeda, Marja Jäättelä   +4 more
doaj   +1 more source

The Concept of Death in John Donne and Sohrab Sepehri: A Comparative Study [PDF]

, 2017
Death has always permeated human’s thoughts at all levels. This preoccupation with death is manifested in the realm of literature. John Donne is one of the artists whose obsession with death is universally recognized.
Behnam Mirzababazadeh Fomeshi
core   +2 more sources

Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis

Cell Death and Disease, 2021
Ferroptosis is a type of regulated cell death characterized by ROS accumulation and devastating lipid peroxidation (LPO). The role of acid sphingomyelinase (ASM), a key enzyme in sphingolipid metabolism, in the induction of apoptosis has been studied ...
Faisal Thayyullathil, Anees Rahman Cheratta, Ameer Alakkal, Karthikeyan Subburayan, Siraj Pallichankandy, Yusuf A. Hannun, Sehamuddin Galadari   +6 more
doaj   +1 more source

Ferroptosis: friend or foe in cancer immunotherapy?

OncoImmunology, 2023
Ferroptosis has gained interest due to it immunogenicity and the higher sensitivity of cancer cells to it. However, it was recently shown that ferroptosis in tumor-associated neutrophils leads to immunosuppression and negatively impacts therapy. Here, we
Robin Demuynck, Iuliia Efimova, Elena Catanzaro, Dmitri V Krysko   +3 more
doaj   +1 more source

Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines

Cell Death and Disease, 2021
Sorafenib, a protein kinase inhibitor approved for the treatment of hepatocellular carcinoma and advanced renal cell carcinoma, has been repeatedly reported to induce ferroptosis by possibly involving inhibition of the cystine/glutamate antiporter, known
Jiashuo Zheng, Mami Sato, Eikan Mishima, Hideyo Sato, Bettina Proneth, Marcus Conrad   +5 more
doaj   +1 more source

Controls on the spatial distribution of oceanic δ¹³C_DIC [PDF]

, 2013
We describe the design and evaluation of a large ensemble of coupled climate–carbon cycle simulations with the Earth system model of intermediate complexity GENIE.
Death, R. M., Edwards, N. R., Holden, P. B., Müller, S. A., Oliver, K. I. C., Ridgwell, A.   +5 more
core   +3 more sources

Definition of Sudden Infant Death and Sudden Intrauterine Unexpected Death Syndromes (SIDS and SIUDS) with Regard to the Anatomo-Pathological Examination

Frontiers in Pediatrics, 2016
Crib death, or sudden infant death syndrome (SIDS), is the most frequent form of death in the first year of life, striking one baby in every 1,700–2,000.
Giulia Ottaviani
doaj   +1 more source

Evolution from a hinge actuator mechanism to an antenna deployment mechanism for use on the European large communications satellite (L-SAT/OLYMPUS) [PDF]

, 1984
The evolution of an Antenna Deployment Mechanism (ADM) from a Hinge Actuator Mechanism (HAM) is described as it pertains to the deployment of large satellite antennas.
Death, M. D.
core   +1 more source