Results 21 to 30 of about 4,987,614 (290)

Buddhism, Brain Death and Organ Transplantation [PDF]

open access: yes, 2010
This article raises concerns about the degree to which potential donors are aware that their layman‖s understanding of death may not be the same as that enshrined in protocols employing the criterion of brain death.
Keown, Damien V.
core   +7 more sources

PTEN-lipid Binding Assay

open access: yesBio-Protocol, 2013
The lipid and protein interactions are an integral and important part of many cellular signaling pathways. The understanding of the selective and specific interaction of the given lipid molecule with the target protein is required for studying cellular ...
Sridhar Kavela   +2 more
doaj   +1 more source

Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics

open access: yesOncoImmunology, 2017
The expression “immunogenic cell death” (ICD) refers to a functionally unique form of cell death that facilitates (instead of suppressing) a T cell-dependent immune response specific for dead cell-derived antigens. ICD critically relies on the activation
Abhishek D. Garg   +8 more
doaj   +1 more source

Macrophage biology plays a central role during ionizing radiation-elicited tumor response

open access: yesBiomedical Journal, 2017
Radiation therapy is one of the major therapeutic modalities for most solid tumors. The anti-tumor effect of radiation therapy consists of the direct tumor cell killing, as well as the modulation of tumor microenvironment and the activation of immune ...
Qiuji Wu   +5 more
doaj   +1 more source

Copy Number Variation and Structural Genomic Findings in 116 Cases of Sudden Unexplained Death between 1 and 28 Months of Age

open access: yesAdvanced Genetics, 2023
In sudden unexplained death in pediatrics (SUDP) the cause of death is unknown despite an autopsy and investigation. The role of copy number variations (CNVs) in SUDP has not been well‐studied. Chromosomal microarray (CMA) data are generated for 116 SUDP
Catherine A. Brownstein   +14 more
doaj   +1 more source

“Mum, when we die, what do you think happens?” A qualitative study of views on death education among Spanish families

open access: yes, 2023
We developed a study to determine perceptions of death education among parents of Spanish schoolchildren aged 3–18 years. We used a qualitative approach, using focus groups and interviews in six state schools.
Herrán Gascón, Agustín de la   +3 more
core   +1 more source

Cell-in-cell structure mediates in-cell killing suppressed by CD44

open access: yesCell Discovery, 2022
Penetration of immune cells into tumor cells was believed to be immune-suppressive via cell-in-cell (CIC) mediated death of the internalized immune cells.
Yan Su   +17 more
doaj   +1 more source

Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis

open access: yesCell Death and Disease, 2021
Ferroptosis is a type of regulated cell death characterized by ROS accumulation and devastating lipid peroxidation (LPO). The role of acid sphingomyelinase (ASM), a key enzyme in sphingolipid metabolism, in the induction of apoptosis has been studied ...
Faisal Thayyullathil   +6 more
doaj   +1 more source

Regulation of Ferroptotic Cancer Cell Death by GPX4

open access: yesCell, 2014
SUMMARY Ferroptosis is a form of nonapoptotic cell death for which key regulators remain unknown. We sought a common mediator for the lethality of 12 ferroptosisinducing small molecules.
W. Yang   +14 more
semanticscholar   +1 more source

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