Results 81 to 90 of about 845,615 (299)

Treating the patient not just the disease? : Delving deeper into the possible link between affective disorders and coronary heart disease through statistical analysis of a random sample of Maltese people [PDF]

, 2014
Background: Ischemic heart disease is the leading cause of death in Males in Malta and globally. Affective disorders are the commonest psychological problem.
Calleja, Neville, Debono, David
core  

Existential distress in cancer: Alleviating suffering from fundamental loss and change [PDF]

, 2018
A severe life threatening illness can challenge fundamental expectations about security, interrelatedness with others, justness, controllability, certainty, and hope for a long and fruitful life.
Kissane, David, Vehling, Sigrun
core   +2 more sources

COVID-19 Anxiety and Death Anxiety: The Predicting Role of Death Anxiety

Cyprus Turkish Journal of Psychiatry and Psychology
The primary aim of this study is to examine the relationship between COVID-19 anxiety and death anxiety among adults in the post-pandemic period. Additionally, the study aims to adapt the COVID-19 Anxiety Scale into Turkish and evaluate its psychometric properties. This research was conducted within the framework of the relational screening model.
Zeynep Demirtaş, Nihan Arslan, Serhat Arslan, Aslı Kartol, Salih Sarışık   +4 more
openaire   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Putting the terror in terror management theory: evidence that the awareness of death does cause anxiety and undermine psychological well-being

, 2016
Rooted in the writings of existentialists, terror management theory states that the awareness of death has the potential to create debilitating anxiety and compromise psychological well-being and that psychological buffers (e.g., self-worth) protect ...
Juhl, Jacob, Routledge, Clay
core   +1 more source

Seeing and holding baby: Systematic review of clinical management and parental outcomes following stillbirth [PDF]

, 2015
Background - In 2009 there were an estimated 2.6 million stillbirths worldwide. In the United States, a 2007 systematic review found little consensus about professional behaviours perceived by parents to be most helpful or most distressing. In the United
Bach Hughes, Bennett, Bonnette, Cacciatore, Cacciatore, Cacciatore, Cacciatore, Cacciatore, Cacciatore, Cahen, Chan, Confidential enquiry into maternal child health, Cousens, Crawley, Downe, Downe, Downe, Erlandsson, Glenton, Gold, Gold, Hughes, Jonas-Simpson, Kavanaugh, Kelley, Kellner, Kohner, Koopmans, Kuti, Lasker, Lathrop, Lee, Lovell, Mays, Moher, Rand, Roehrs, Rådestad, Rådestad, Rådestad, Samuelsson, Steen, Surkan, Säflund, Thompson, Trulsson, Turton, Wallbank, Walsh, Warland, Worth, Yamazaki   +51 more
core   +1 more source

Death Anxiety and Psychopathology

Research across various psychology disciplines underscores death anxiety as a significant construct. Numerous tools assess death anxiety, but many have questionable psychometric properties. To address these shortcomings, the Death Anxiety Beliefs and Behaviours Scale (DABBS) was developed, which also assesses death-related maladaptive beliefs and ...
null Mazidi, Majdi Zarei, Ziba Ahmadi Bouyaghchi, Seyran Ranjbar, Rachel E Menzies   +4 more
openaire   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source

Can We Really Prevent Suicide? [PDF]

, 2012
Every year, suicide is among the top 20 leading causes of death globally for all ages. Unfortunately, suicide is difficult to prevent, in large part because the prevalence of risk factors is high among the general population. In this review, clinical and
A Fagiolini, A Roy, A Roy, AC Leon, AD Lopez, AF Jorm, AL Beautrais, AN Sabo, AP Chioqueta, B Schneider, B Schneider, B Spivac, B Stanely, B Stanley, B Yerevanian, BA Palmer, BN Gaynes, C Bushe, C Haw, CM Feltz-Cornelis van der, CW Tsai, D Fergusson, D Gunnell, D Shaffer, D Wasserman, DA Brent, DA Brent, DA Brent, EC Harris, F Cassidy, F Guzzetta, F Keller, FK Goodwin, FS Bridges, G Dieserud, G Isacsson, G Isacsson, G Sonneck, Gil Zalsman, GK Brown, GL Carter, GL Sidley, H Dumesnil, H Galfalvy, H Valtonen, HG Morgan, HJ Moller, HJ Moller, HJ Moller, HY Meltzer, J Fawcet, J Johnson, J Lonnqvist, JA Egeland, JB Luoma, JD Maser, JJ Lin, JJ Mann, JJ Mann, JM Boden, JMG Williams, K Hawton, K Hor, K Posner, K Szanto, KL Knox, KM Malone, L Tondo, LM Hayes, Lucas Giner, M Bauer, M Bauer, M Leitner, M Miller, M Olfson, M Panagioti, M Pompili, M Sarchiapone, M Shelef, MA Oquendo, MA Oquendo, MA Oquendo, MA Oquendo, Maria A. Oquendo, Maya Schwartz-Lifshitz, MD Rudd, MM Linehan, MP Pignone, N Tarrier, ND Kapusta, NM Melhem, O Bennewith, PA Wyman, PG Placidi, PH Soloff, PH Soloff, RD Gibbons, RJ Baldessarini, S Kelly, SH Kennedy, SP Pirkola, U Hegerl, U Hegerl, U Hegerl, UA Andersen, W Coryell, WA Watson, WD Hall, Z Rihmer, Z Rihmer, Z Rihmer, Z Rihmer   +111 more
core   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source